Structured evidence table for Saffron Stress Support Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Saffron Stress Support Randomized Trial | Conclusion The findings of this meta-analysis provide compelling evidence to support the efficacy of saffron supplementation in reducing the effects of TNF-α levels in individuals with T2DM. | 1 | Qin L (2025) | The efficacy of saffron supplementation on inflammation and oxidative stress in patients with type-2 diabetes mellitus: a meta-analysis. |
| Saffron Stress Support Randomized Trial | Background In this study, a meta-analysis was performed to evaluate the changes in the levels of inflammation and oxidative stress levels in type 2 diabetes mellitus (T2DM) patients after saffron supplementation. | 1 | Qin L (2025) | The efficacy of saffron supplementation on inflammation and oxidative stress in patients with type-2 diabetes mellitus: a meta-analysis. |
| Saffron Stress Support Randomized Trial | Methods A comprehensive and systematic investigation was carried out to identify relevant studies on PubMed, Web of Science, The Cochrane Library, and EMBASE databases. | 1 | Qin L (2025) | The efficacy of saffron supplementation on inflammation and oxidative stress in patients with type-2 diabetes mellitus: a meta-analysis. |
| Saffron Stress Support Randomized Trial | Behavioral analysis revealed that cold stress significantly impaired memory and increased anxiety-like behavior, whereas oral supplementation of saffron extract reduced anxiety, improved spontaneous alternation and enhanced object recognition memory. | 4 | Priya V (2026) | <i>Crocus sativus</i> improves cognitive functions and reduces anxiety-like behavior in aged rats exposed to chronic cold temperature-induced stress. |
| Saffron Stress Support Randomized Trial | Conclusion Saffron extract enhances neurobehavioral functions, significantly ameliorating cold stress-induced cognitive deficits and anxiety-like behavior. | 4 | Priya V (2026) | <i>Crocus sativus</i> improves cognitive functions and reduces anxiety-like behavior in aged rats exposed to chronic cold temperature-induced stress. |
| Saffron Stress Support Randomized Trial | Introduction Chronic cold stress acts as an influential environmental stressor that disrupts neuro-behavioral functions, which include anxiety responses, cognitive performance, mood regulation, and stress susceptibility. | 4 | Priya V (2026) | <i>Crocus sativus</i> improves cognitive functions and reduces anxiety-like behavior in aged rats exposed to chronic cold temperature-induced stress. |
| Saffron Stress Support Randomized Trial | In spite of the growing recognition of cold-induced neuropathology, effective therapeutic strategies remain limited. | 4 | Priya V (2026) | <i>Crocus sativus</i> improves cognitive functions and reduces anxiety-like behavior in aged rats exposed to chronic cold temperature-induced stress. |
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