topicSaffron Premenstrual Syndrome Randomized Trial
claimDifficulties in accessing healthcare, their high costs, personal preferences, and the perceived safety of medicinal herbs have contributed to the increased usage of herbalism [,,].
evidence level1
citationHasheminasab Fatemeh Sadat (2026)
sourceAdverse Events of Saffron ( Crocus sativus L.): Systematic Review of Current Evidence
topicSaffron Premenstrual Syndrome Randomized Trial
claimGiven their popularity, it is crucial to have up‐to‐date risk and benefit assessments on these herbal products [].
evidence level1
citationHasheminasab Fatemeh Sadat (2026)
sourceAdverse Events of Saffron ( Crocus sativus L.): Systematic Review of Current Evidence
topicSaffron Premenstrual Syndrome Randomized Trial
claimTherefore, compiling a systematic review of human studies with the aim of summarizing the available evidence on the side effects ofnot only fills the gap in the literature but also seems essential for physicians, researchers, and health policymakers to use this widely used medicinal plant safely and rationally.
evidence level1
citationHasheminasab Fatemeh Sadat (2026)
sourceAdverse Events of Saffron ( Crocus sativus L.): Systematic Review of Current Evidence
topicSaffron Premenstrual Syndrome Randomized Trial
claimsativus 1 1 2 2 3 Saffron (L.) is a sophisticated spice with culinary and therapeutic importance [].
evidence level1
citationHasheminasab Fatemeh Sadat (2026)
sourceAdverse Events of Saffron ( Crocus sativus L.): Systematic Review of Current Evidence
topicSaffron Premenstrual Syndrome Randomized Trial
claimA Swiss study found that 10% of participants experienced PMS, whereas 3% experienced PMDD.
evidence level1
citationMohammadi Mohammad Mehdi (2026)
sourceEffect of saffron on premenstrual syndrome and dysmenorrhea: a systematic review and meta-analysis
topicSaffron Premenstrual Syndrome Randomized Trial
claimThese challenges include legal issues, suicidal ideation, reduced work productivity, social isolation, parenting difficulties, increased absenteeism, disruptions of personal and social relationships, and frequent hospital visits.
evidence level1
citationMohammadi Mohammad Mehdi (2026)
sourceEffect of saffron on premenstrual syndrome and dysmenorrhea: a systematic review and meta-analysis
topicSaffron Premenstrual Syndrome Randomized Trial
claimPMS and dysmenorrhea can also contribute to increased susceptibility to accidents, drug addiction, financial losses, and diminished achievements [].
evidence level1
citationMohammadi Mohammad Mehdi (2026)
sourceEffect of saffron on premenstrual syndrome and dysmenorrhea: a systematic review and meta-analysis
topicSaffron Premenstrual Syndrome Randomized Trial
claim1 2 2 3 1 4 5 6 Premenstrual syndrome (PMS) refers to a range of psychological, emotional and behavioral symptoms that occur prior to menstruation [].
evidence level1
citationMohammadi Mohammad Mehdi (2026)
sourceEffect of saffron on premenstrual syndrome and dysmenorrhea: a systematic review and meta-analysis