Structured evidence table for Saffron Mood Support Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Saffron Mood Support Randomized Trial | Background/Objectives: The global prevalence of mental health disorders, particularly anxiety and depression, has increased significantly, with rates further elevated by the COVID-19 pandemic. | 2 | Dormal V (2025) | The Effects of Combined Scutellaria and Saffron Supplementation on Mood Regulation in Participants with Mild-to-Moderate Depressive Symptoms: A Randomized, Double-Blind, Placebo-Controlled Study. |
| Saffron Mood Support Randomized Trial | Conventional pharmacological treatments, while effective, often lead to side effects that can impact patient adherence and quality of life. | 2 | Dormal V (2025) | The Effects of Combined Scutellaria and Saffron Supplementation on Mood Regulation in Participants with Mild-to-Moderate Depressive Symptoms: A Randomized, Double-Blind, Placebo-Controlled Study. |
| Saffron Mood Support Randomized Trial | Behavioral analysis revealed that cold stress significantly impaired memory and increased anxiety-like behavior, whereas oral supplementation of saffron extract reduced anxiety, improved spontaneous alternation and enhanced object recognition memory. | 4 | Priya V (2026) | <i>Crocus sativus</i> improves cognitive functions and reduces anxiety-like behavior in aged rats exposed to chronic cold temperature-induced stress. |
| Saffron Mood Support Randomized Trial | Conclusion Saffron extract enhances neurobehavioral functions, significantly ameliorating cold stress-induced cognitive deficits and anxiety-like behavior. | 4 | Priya V (2026) | <i>Crocus sativus</i> improves cognitive functions and reduces anxiety-like behavior in aged rats exposed to chronic cold temperature-induced stress. |
| Saffron Mood Support Randomized Trial | Introduction Chronic cold stress acts as an influential environmental stressor that disrupts neuro-behavioral functions, which include anxiety responses, cognitive performance, mood regulation, and stress susceptibility. | 4 | Priya V (2026) | <i>Crocus sativus</i> improves cognitive functions and reduces anxiety-like behavior in aged rats exposed to chronic cold temperature-induced stress. |
| Saffron Mood Support Randomized Trial | In spite of the growing recognition of cold-induced neuropathology, effective therapeutic strategies remain limited. | 4 | Priya V (2026) | <i>Crocus sativus</i> improves cognitive functions and reduces anxiety-like behavior in aged rats exposed to chronic cold temperature-induced stress. |
Source documents