Structured evidence table for Saffron Depression Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Saffron Depression Randomized Trial | This narrative review critically evaluates clinical evidence on commonly used herbal preparations, with particular emphasis on herb-drug interactions, adverse effects, and issues related to product adulteration. | 3 | Căuș MN (2026) | Efficacy and Safety of Herbal Supplements with Anxiolytic, Antidepressant, and Sedative Action: A Review of Clinical Data and Toxicological Risks. |
| Saffron Depression Randomized Trial | However, clinically relevant risks were identified, including cytochrome P450-mediated drug interactions, excessive sedation, serotonin syndrome, and toxic effects associated with adulterated products, such as hepatotoxicity, cardiovascular events, and neurological disturbances. | 3 | Căuș MN (2026) | Efficacy and Safety of Herbal Supplements with Anxiolytic, Antidepressant, and Sedative Action: A Review of Clinical Data and Toxicological Risks. |
| Saffron Depression Randomized Trial | Increased awareness of herb-drug interactions and stricter quality control are essential to optimize therapeutic outcomes and minimize harm. | 3 | Căuș MN (2026) | Efficacy and Safety of Herbal Supplements with Anxiolytic, Antidepressant, and Sedative Action: A Review of Clinical Data and Toxicological Risks. |
| Saffron Depression Randomized Trial | Background/Objectives: Plant-based supplements are widely used for the management of anxiety, depression, and insomnia. | 3 | Căuș MN (2026) | Efficacy and Safety of Herbal Supplements with Anxiolytic, Antidepressant, and Sedative Action: A Review of Clinical Data and Toxicological Risks. |
| Saffron Depression Randomized Trial | In this review, we want to systematically sort out the evidence about the antidepressant effects of five main culinary spices: turmeric, saffron, ginger, chili pepper and black pepper. | 3 | Zhong Lu (2026) | Mood food: antidepressant effects of culinary spices |
| Saffron Depression Randomized Trial | 34 36 37 38 Now there is more and more evidence that depression is actually a systemic inflammatory problem, people with MDD have a higher comorbidity rate with immune and inflammatory diseases such as rheumatoid arthritis, metabolic syndrome, and inflammatory bowel disease (–). | 3 | Zhong Lu (2026) | Mood food: antidepressant effects of culinary spices |
| Saffron Depression Randomized Trial | A large number of animal experiments have found that curcumin has similar antidepressant effects in several commonly used animal models of depression, such as olfactory bulbectomy, corticosterone-induced stress, and monoamine depletion caused by reserpine (). | 3 | Zhong Lu (2026) | Mood food: antidepressant effects of culinary spices |
| Saffron Depression Randomized Trial | 1 2 3 4 5 6 7 10 Depressive has become the main causes of global disease burden, causing great disability and health problems worldwide (). | 3 | Zhong Lu (2026) | Mood food: antidepressant effects of culinary spices |
Source documents