topicSaffron Attention Randomized Trial
claimDifficulties in accessing healthcare, their high costs, personal preferences, and the perceived safety of medicinal herbs have contributed to the increased usage of herbalism [,,].
evidence level1
citationHasheminasab Fatemeh Sadat (2026)
sourceAdverse Events of Saffron ( Crocus sativus L.): Systematic Review of Current Evidence
topicSaffron Attention Randomized Trial
claimGiven their popularity, it is crucial to have up‐to‐date risk and benefit assessments on these herbal products [].
evidence level1
citationHasheminasab Fatemeh Sadat (2026)
sourceAdverse Events of Saffron ( Crocus sativus L.): Systematic Review of Current Evidence
topicSaffron Attention Randomized Trial
claimTherefore, compiling a systematic review of human studies with the aim of summarizing the available evidence on the side effects ofnot only fills the gap in the literature but also seems essential for physicians, researchers, and health policymakers to use this widely used medicinal plant safely and rationally.
evidence level1
citationHasheminasab Fatemeh Sadat (2026)
sourceAdverse Events of Saffron ( Crocus sativus L.): Systematic Review of Current Evidence
topicSaffron Attention Randomized Trial
claimsativus 1 1 2 2 3 Saffron (L.) is a sophisticated spice with culinary and therapeutic importance [].
evidence level1
citationHasheminasab Fatemeh Sadat (2026)
sourceAdverse Events of Saffron ( Crocus sativus L.): Systematic Review of Current Evidence
topicSaffron Attention Randomized Trial
claimIn recent years, a growing body of scientific evidence supporting several of these traditional uses has shown the potential of saffron and its main ingredients—crocins, crocetin, safranal, and picrocrocin—as pharmacologically relevant compounds.
evidence level3
citationCampos Catarina (2026)
sourceFrom Stigma to Therapy: Pharmacological Insights into Saffron Bioactives for Major Non-Communicable Diseases
topicSaffron Attention Randomized Trial
claimBy integrating evidence from in vitro studies, animal models, and clinical trials, this review critically assesses saffron’s potential as a multi-target pharmacological agent and identifies key limitations and future directions for its development within pharmaceutical and integrative medicine frameworks.
evidence level3
citationCampos Catarina (2026)
sourceFrom Stigma to Therapy: Pharmacological Insights into Saffron Bioactives for Major Non-Communicable Diseases
topicSaffron Attention Randomized Trial
claimConsidering the scope of disease areas covered, this review is intended to be a broad narrative overview rather than an exhaustive systematic evaluation of each disease, with a focus on critically evaluating study quality, level of evidence, gaps between preclinical findings and clinical applicability, and limitations across sections.
evidence level3
citationCampos Catarina (2026)
sourceFrom Stigma to Therapy: Pharmacological Insights into Saffron Bioactives for Major Non-Communicable Diseases
topicSaffron Attention Randomized Trial
claimCrocus sativus 1 2 3 4 5 6 Natural products remain one of the main sources of pharmacologically bioactive compounds (BACs) and have played a fundamental role in the development of new drugs.
evidence level3
citationCampos Catarina (2026)
sourceFrom Stigma to Therapy: Pharmacological Insights into Saffron Bioactives for Major Non-Communicable Diseases