Structured evidence table for Saffron Appetite Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Saffron Appetite Randomized Trial | However, due to some potentially significant adverse events associated with its medicinal use at higher doses or prolonged administration, clinical monitoring should be considered. | 1 | Hasheminasab FS (2026) | Adverse Events of Saffron (<i>Crocus sativus</i> L.): Systematic Review of Current Evidence. |
| Saffron Appetite Randomized Trial | Background Crocus sativus L., commonly known as saffron, is a widely used spice with a rich history of culinary and medicinal applications. | 1 | Hasheminasab FS (2026) | Adverse Events of Saffron (<i>Crocus sativus</i> L.): Systematic Review of Current Evidence. |
| Saffron Appetite Randomized Trial | This systematic review aims to compile human data from studies on monopreparations of C. | 1 | Hasheminasab FS (2026) | Adverse Events of Saffron (<i>Crocus sativus</i> L.): Systematic Review of Current Evidence. |
| Saffron Appetite Randomized Trial | Dysregulated adipogenesis in obesity involves excessive preadipocyte recruitment and differentiation, leading to increased adipocyte number (hyperplasia) and hypertrophy. | 3 | Marie Ohoud M. (2026) | Obesity and Natural Products: Mechanisms, Therapeutic Potential, and Future Directions |
| Saffron Appetite Randomized Trial | In obesity, lipolytic capacity is suppressed through multiple mechanisms including impaired sympathetic nervous system signaling and reduced expression of lipolytic enzymes (Thorp and Schlaich ). | 3 | Marie Ohoud M. (2026) | Obesity and Natural Products: Mechanisms, Therapeutic Potential, and Future Directions |
| Saffron Appetite Randomized Trial | At the molecular level, obesity‐associated chronic inflammation and elevated circulating free fatty acids impair leptin signaling through the hypothalamic leptin receptor (Jais and Brüning ). | 3 | Marie Ohoud M. (2026) | Obesity and Natural Products: Mechanisms, Therapeutic Potential, and Future Directions |
| Saffron Appetite Randomized Trial | 2025 2025 2025 2025 2023 Obesity represents one of the most pressing public health challenges of the 21st century, characterized by excessive accumulation of adipose tissue that impairs health and quality of life (Ahmed and Mohammed ; Lewandowska et al. ). | 3 | Marie Ohoud M. (2026) | Obesity and Natural Products: Mechanisms, Therapeutic Potential, and Future Directions |
Source documents