Saffron Anxiety Randomized Trial Evidence Table

Structured evidence table for Saffron Anxiety Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Saffron Anxiety Randomized TrialHowever, due to some potentially significant adverse events associated with its medicinal use at higher doses or prolonged administration, clinical monitoring should be considered.1Hasheminasab FS (2026)Adverse Events of Saffron (<i>Crocus sativus</i> L.): Systematic Review of Current Evidence.
Saffron Anxiety Randomized TrialBackground Crocus sativus L., commonly known as saffron, is a widely used spice with a rich history of culinary and medicinal applications.1Hasheminasab FS (2026)Adverse Events of Saffron (<i>Crocus sativus</i> L.): Systematic Review of Current Evidence.
Saffron Anxiety Randomized TrialThis systematic review aims to compile human data from studies on monopreparations of C.1Hasheminasab FS (2026)Adverse Events of Saffron (<i>Crocus sativus</i> L.): Systematic Review of Current Evidence.
Saffron Anxiety Randomized TrialThis narrative review critically evaluates clinical evidence on commonly used herbal preparations, with particular emphasis on herb-drug interactions, adverse effects, and issues related to product adulteration.3Căuș MN (2026)Efficacy and Safety of Herbal Supplements with Anxiolytic, Antidepressant, and Sedative Action: A Review of Clinical Data and Toxicological Risks.
Saffron Anxiety Randomized TrialHowever, clinically relevant risks were identified, including cytochrome P450-mediated drug interactions, excessive sedation, serotonin syndrome, and toxic effects associated with adulterated products, such as hepatotoxicity, cardiovascular events, and neurological disturbances.3Căuș MN (2026)Efficacy and Safety of Herbal Supplements with Anxiolytic, Antidepressant, and Sedative Action: A Review of Clinical Data and Toxicological Risks.
Saffron Anxiety Randomized TrialIncreased awareness of herb-drug interactions and stricter quality control are essential to optimize therapeutic outcomes and minimize harm.3Căuș MN (2026)Efficacy and Safety of Herbal Supplements with Anxiolytic, Antidepressant, and Sedative Action: A Review of Clinical Data and Toxicological Risks.
Saffron Anxiety Randomized TrialBackground/Objectives: Plant-based supplements are widely used for the management of anxiety, depression, and insomnia.3Căuș MN (2026)Efficacy and Safety of Herbal Supplements with Anxiolytic, Antidepressant, and Sedative Action: A Review of Clinical Data and Toxicological Risks.

Source documents

  1. Adverse Events of Saffron (<i>Crocus sativus</i> L.): Systematic Review of Current Evidence.
  2. Efficacy and Safety of Herbal Supplements with Anxiolytic, Antidepressant, and Sedative Action: A Review of Clinical Data and Toxicological Risks.