topicRoyal Jelly Supplement Energy Randomized Trial
claimPhenolic acids are bioactive components found at a rate of approximately 0.19% in pollen.
evidence level3
citationSanlier Nevin (2026)
sourceHealth Effects of Bee Products: A Comprehensive Review
topicRoyal Jelly Supplement Energy Randomized Trial
claimIt is formed as a result of the fermentation of bee pollen with various digestive enzymes and honey (Mărgăoan et al. ).
evidence level3
citationSanlier Nevin (2026)
sourceHealth Effects of Bee Products: A Comprehensive Review
topicRoyal Jelly Supplement Energy Randomized Trial
claimAlthough the outer layer of pollen cannot be digested in the stomach under normal conditions, the outer layer of the pollen dissolves as a result of pollen fermentation and the substances in the pollen can be absorbed more easily (Bakour et al. ).
evidence level3
citationSanlier Nevin (2026)
sourceHealth Effects of Bee Products: A Comprehensive Review
topicRoyal Jelly Supplement Energy Randomized Trial
claimAD ARC CAPE CRP DBH EFSA HDL‐C HMF IL‐6 LDL‐C MetS NAFLD PAPP PLA2 ROS T2DM TC TNF‐α USDA WHO 2021 2021 2020a For over 5500 years, bee‐derived products have been recognized for both their nutritional value and their healing properties.
evidence level3
citationSanlier Nevin (2026)
sourceHealth Effects of Bee Products: A Comprehensive Review
topicRoyal Jelly Supplement Energy Randomized Trial
claimMoreover, studies in recent years have shown that phytochemicals can mitigate oxidative stress and inflammation in critically ill patients (Malekahmadi et al. ; Pahlavani et al. ), improve exercise performance in athletes (Putera et al. ), and reduce cardiometabolic risk factors in the general population (Jandari et al. ).
evidence level4
citationPasdar Yahya (2025)
sourceRoyal Jelly Supplementation Improves Endurance and Mitochondrial Biogenesis in Athletes: A Crossover Trial
topicRoyal Jelly Supplement Energy Randomized Trial
claimMeta‐analytic evidence from clinical trials has shown that RJ can be a safe and effective dietary supplement for controlling glycemia in diabetic patients (Bahari, Taheri, Rashidmayvan, Hezaveh, et al. ; Bahari, Taheri, Rashidmayvan, Jamshidi, et al. ).
evidence level4
citationPasdar Yahya (2025)
sourceRoyal Jelly Supplementation Improves Endurance and Mitochondrial Biogenesis in Athletes: A Crossover Trial
topicRoyal Jelly Supplement Energy Randomized Trial
claimMoreover, the latest findings revealed that the administration of RJ can decrease the risk of cardiovascular diseases (Bahari, Taheri, Rashidmayvan, Hezaveh, et al. ; Bahari, Taheri, Rashidmayvan, Jamshidi, et al. ) and alleviate gastrointestinal diseases (El‐Seedi et al. ).
evidence level4
citationPasdar Yahya (2025)
sourceRoyal Jelly Supplementation Improves Endurance and Mitochondrial Biogenesis in Athletes: A Crossover Trial
topicRoyal Jelly Supplement Energy Randomized Trial
claim2020 2010 2015 2024 2024 2021 2022 2023 2020 Mitochondria mainly contribute to supplying the energy requirements for muscle contraction through the oxidative phosphorylation pathway.
evidence level4
citationPasdar Yahya (2025)
sourceRoyal Jelly Supplementation Improves Endurance and Mitochondrial Biogenesis in Athletes: A Crossover Trial