topicRoyal Jelly Skin Health Randomized Trial
claimDespite encouraging preclinical and in vitro findings, substantial research gaps remain, and most pieces of evidence are derived from animal studies or small-scale clinical trials that lack sample sizes, standardized methodologies, or long-term follow-up.
evidence level3
citationRawwash Ahmed A. (2025)
sourceBee Products and Traditional Plant Therapies for Wound Care: a comprehensive review of scientific evidence and clinical applications
topicRoyal Jelly Skin Health Randomized Trial
claimStudies published in English between 2000 and 2025, specifically peer-reviewed articles that presented in vitro, in vivo, or clinical evidence related to wound care, were included.
evidence level3
citationRawwash Ahmed A. (2025)
sourceBee Products and Traditional Plant Therapies for Wound Care: a comprehensive review of scientific evidence and clinical applications
topicRoyal Jelly Skin Health Randomized Trial
claimAlthough many studies have indicated that bee products and traditional plant therapies are effective wound healers, most pieces of evidence were from preclinical research or small-scale clinical trials, thereby limiting generalizability.
evidence level3
citationRawwash Ahmed A. (2025)
sourceBee Products and Traditional Plant Therapies for Wound Care: a comprehensive review of scientific evidence and clinical applications
topicRoyal Jelly Skin Health Randomized Trial
claim1 2 3 Skin wounds are considered a global issue because of their high morbidity and treatment costs.
evidence level3
citationRawwash Ahmed A. (2025)
sourceBee Products and Traditional Plant Therapies for Wound Care: a comprehensive review of scientific evidence and clinical applications
topicRoyal Jelly Skin Health Randomized Trial
claimA diminished ovarian reserve (DOR) refers to a reduction in the number of recruitable follicles in the ovaries or a decline in oocyte quality, leading to decreased gamete production and reduced fertility.
evidence level4
citationPi Xiangyou (2026)
sourceSpontaneous pregnancy in a woman with diminished ovarian reserve following dietary supplementation with major royal jelly proteins: A case report
topicRoyal Jelly Skin Health Randomized Trial
claimIn China, due to delayed childbearing, the 2-child policy, and social environmental factors, the proportion of patients with DOR is increasing, accounting for 10% of infertile women.In recent years, the prevalence of infertility has continually increased from 12% in 2007 to 18% in 2020 in China.
evidence level4
citationPi Xiangyou (2026)
sourceSpontaneous pregnancy in a woman with diminished ovarian reserve following dietary supplementation with major royal jelly proteins: A case report
topicRoyal Jelly Skin Health Randomized Trial
claimHowever, with advances in assisted reproductive technology, the success rate of infertility treatment has increased from 26% in 1990 to 40% to 60% in 2020.
evidence level4
citationPi Xiangyou (2026)
sourceSpontaneous pregnancy in a woman with diminished ovarian reserve following dietary supplementation with major royal jelly proteins: A case report
topicRoyal Jelly Skin Health Randomized Trial
claimAdditionally, MRJPs elevate the uterine and ovarian indices and promote follicular development.
evidence level4
citationPi Xiangyou (2026)
sourceSpontaneous pregnancy in a woman with diminished ovarian reserve following dietary supplementation with major royal jelly proteins: A case report