topicRosemary Memory Randomized Trial
claimNational dietary guidelines from several countries (eg, the United States, United Kingdom, and Australia) recommend the consumption of spices to lower sodium intake.The National Institutes of Health (NIH)–funded Dietary Approaches to Stop Hypertension (DASH) healthy eating plan replaces salt with spices and herbs as a means to lower blood pressure without medication.
evidence level3
citationDiacova Tatiana (2026)
sourceSpices Beyond Antioxidants: From the Gut to the Brain
topicRosemary Memory Randomized Trial
claimIt was also demonstrated that salt intake was associated with regional metabolic activity in the insula and orbitofrontal cortex (OFC) areas of the brain.The administration of capsaicin (chili pepper) in the Li et al.
evidence level3
citationDiacova Tatiana (2026)
sourceSpices Beyond Antioxidants: From the Gut to the Brain
topicRosemary Memory Randomized Trial
claim(2013) To investigate whether spice (poly)phenols reduce GI and systemic formation of cytotoxic lipid peroxidation products and increase NO formation, thereby leading to improved endothelial vascular function n  = 11 men with type 2 diabetes RCT 2 test meals, 1 wk apart  Zhang et al.
evidence level3
citationDiacova Tatiana (2026)
sourceSpices Beyond Antioxidants: From the Gut to the Brain
topicRosemary Memory Randomized Trial
claimHerbs and spices have been used in various countries around the world for centuries.
evidence level3
citationDiacova Tatiana (2026)
sourceSpices Beyond Antioxidants: From the Gut to the Brain
topicRosemary Memory Randomized Trial
claimThis study consolidates the evidence based on phytochemicals for cognitive enhancement, highlighting a need for more robust, methodologically sound trials to determine if these natural compounds hold promise in cognitive therapeutics, particularly for populations with cognitive impairments.
evidence level3
citationMarsh Alexander (2026)
sourceThe efficacy of nutritional phytochemical compounds in improving cognition
topicRosemary Memory Randomized Trial
claimAccordingly, this review prespecified phytochemicals that meet 3 criteria: long-standing traditional association with cognition, biological plausibility supported by preclinical evidence, and progression into human research or commercial cognitive-health formulations, includingL.
evidence level3
citationMarsh Alexander (2026)
sourceThe efficacy of nutritional phytochemical compounds in improving cognition
topicRosemary Memory Randomized Trial
claimWhile the evidence surrounding green tea and its relevant constituents is relatively well summarized, the impact that other herbs and phytochemical compounds may have on cognition remains to be systematically reviewed.
evidence level3
citationMarsh Alexander (2026)
sourceThe efficacy of nutritional phytochemical compounds in improving cognition
topicRosemary Memory Randomized Trial
claimtenuiflorum This study addresses the effectiveness of various naturally occurring molecules in improving cognitive functions in healthy adults.
evidence level3
citationMarsh Alexander (2026)
sourceThe efficacy of nutritional phytochemical compounds in improving cognition