topicRhodiola Stress Randomized Trial
claimThese limitations have catalyzed an increased global focus on nutraceuticals and phytomedicines possessing multimodal biological activities that transcend mere monoamine reuptake inhibition.
evidence level3
citationLi Xikun (2026)
sourceRhodiola rosea , Ginkgo biloba , and Ashwagandha as novel antidepressant supplements: converging monoaminergic, neurotrophic, anti-inflammatory, and brain health pathways in depressive disorders
topicRhodiola Stress Randomized Trial
claimUnlike prior reviews that focus on individual herbs or broadly defined adaptogens, the present review integrates mechanistic, preclinical, and clinical evidence across these three agents to highlight their complementary rather than redundant actions.
evidence level3
citationLi Xikun (2026)
sourceRhodiola rosea , Ginkgo biloba , and Ashwagandha as novel antidepressant supplements: converging monoaminergic, neurotrophic, anti-inflammatory, and brain health pathways in depressive disorders
topicRhodiola Stress Randomized Trial
claimRhodiola rosea Ginkgo biloba Withania somnifera A comprehensive and structured literature search was conducted to identify preclinical, translational, and clinical evidence related to the antidepressant effects and underlying neurobiological mechanisms of,, and(Ashwagandha).
evidence level3
citationLi Xikun (2026)
sourceRhodiola rosea , Ginkgo biloba , and Ashwagandha as novel antidepressant supplements: converging monoaminergic, neurotrophic, anti-inflammatory, and brain health pathways in depressive disorders
topicRhodiola Stress Randomized Trial
claim1 2 3 Rhodiola rosea Ginkgo biloba Withania somnifera Depression constitutes one of the most incapacitating neuropsychiatric disorders globally ().
evidence level3
citationLi Xikun (2026)
sourceRhodiola rosea , Ginkgo biloba , and Ashwagandha as novel antidepressant supplements: converging monoaminergic, neurotrophic, anti-inflammatory, and brain health pathways in depressive disorders
topicRhodiola Stress Randomized Trial
claimSleep is a complex biological process whose evolutionary purpose has remained equivocal for quite some time.More recently, however, compelling evidence has emerged, leading to recognition of the numerous metabolic and physiological functions sleep contributes to and actively supports.
evidence level4
citationConti Federica (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review
topicRhodiola Stress Randomized Trial
claimEpidemiological studies have revealed that sleep deprivation is associated with an increased risk of all-cause mortality,alongside numerous chronic conditions imposing a heavy burden on our healthcare and socioeconomic systems alike,including cardiovascular disease, stroke, obesity, type 2 diabetes, and various types of cancer and neurological disorders.
evidence level4
citationConti Federica (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review
topicRhodiola Stress Randomized Trial
claimThe scope of this narrative review is to summarize the available evidence on the mechanisms of action and potential benefits of the above-listed nutrients in the context of acute or chronic sleep disturbances.
evidence level4
citationConti Federica (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review
topicRhodiola Stress Randomized Trial
claim, , Over the past few decades, there has been an increasing appreciation of the negative impact of sleep disturbances and circadian misalignments on all aspects of human health and performance, ranging from objective alertness, learning, memory, and cognition to emotional regulation, social wellbeing and, most remarkably, physical health.
evidence level4
citationConti Federica (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review