topicResveratrol Inflammation Randomized Trial
claimThe main aim of this systematic review is to comprehensively evaluate and synthesize the current scientific evidence on the role of anthocyanins, curcumin, and resveratrol in the prevention and management of metabolic disorders, with a focus on obesity, type 2 diabetes, and dyslipidemia.
evidence level1
citationGazda P (2026)
sourceThe Role of Anthocyanins, Curcumin, and Resveratrol in the Prevention and Management of Metabolic Disorders: A Systematic Review.
topicResveratrol Inflammation Randomized Trial
claimThe analyzed studies demonstrated that anthocyanin supplementation (up to 320 mg/day) was associated with reductions in inflammatory markers such as IL-6 and TNF-α, improvements in HDL cholesterol, and modest reductions in HbA1c (~0.3-0.5%).
evidence level1
citationGazda P (2026)
sourceThe Role of Anthocyanins, Curcumin, and Resveratrol in the Prevention and Management of Metabolic Disorders: A Systematic Review.
topicResveratrol Inflammation Randomized Trial
claimCurcumin supplementation was associated with decreases in body weight (up to 0.82 kg), BMI (up to 0.30 kg/m 2 ), triglycerides, total cholesterol, and fasting glucose levels.
evidence level1
citationGazda P (2026)
sourceThe Role of Anthocyanins, Curcumin, and Resveratrol in the Prevention and Management of Metabolic Disorders: A Systematic Review.
topicResveratrol Inflammation Randomized Trial
claimMetabolic disorders such as obesity, type 2 diabetes, and lipid disorders are major health challenges worldwide.
evidence level1
citationGazda P (2026)
sourceThe Role of Anthocyanins, Curcumin, and Resveratrol in the Prevention and Management of Metabolic Disorders: A Systematic Review.
topicResveratrol Inflammation Randomized Trial
claimAs a result, no phenotype-defined interventional evidence specific to sarcopenic obesity was identified.
evidence level1
citationRusso C (2026)
sourceVitamin D and resveratrol in sarcopenic obesity: a systematic review highlighting the gap in phenotype-defined randomized controlled trials.
topicResveratrol Inflammation Randomized Trial
claimConclusion Despite compelling mechanistic convergence, randomized interventional evidence in strictly defined sarcopenic obesity populations is currently lacking.
evidence level1
citationRusso C (2026)
sourceVitamin D and resveratrol in sarcopenic obesity: a systematic review highlighting the gap in phenotype-defined randomized controlled trials.
topicResveratrol Inflammation Randomized Trial
claimBackground Sarcopenic obesity (SO) is an inflammatory-metabolic condition characterized by the coexistence of excess adiposity and impaired skeletal muscle mass and function.
evidence level1
citationRusso C (2026)
sourceVitamin D and resveratrol in sarcopenic obesity: a systematic review highlighting the gap in phenotype-defined randomized controlled trials.
topicResveratrol Inflammation Randomized Trial
claimVitamin D and resveratrol modulate regulatory pathways implicated in SO pathophysiology, including NF-κB signaling, PGC-1α, mitochondrial regulation, and redox balance.
evidence level1
citationRusso C (2026)
sourceVitamin D and resveratrol in sarcopenic obesity: a systematic review highlighting the gap in phenotype-defined randomized controlled trials.