topicResveratrol Exercise Performance Randomized Trial
claimAs a result, no phenotype-defined interventional evidence specific to sarcopenic obesity was identified.
evidence level1
citationRusso C (2026)
sourceVitamin D and resveratrol in sarcopenic obesity: a systematic review highlighting the gap in phenotype-defined randomized controlled trials.
topicResveratrol Exercise Performance Randomized Trial
claimConclusion Despite compelling mechanistic convergence, randomized interventional evidence in strictly defined sarcopenic obesity populations is currently lacking.
evidence level1
citationRusso C (2026)
sourceVitamin D and resveratrol in sarcopenic obesity: a systematic review highlighting the gap in phenotype-defined randomized controlled trials.
topicResveratrol Exercise Performance Randomized Trial
claimBackground Sarcopenic obesity (SO) is an inflammatory-metabolic condition characterized by the coexistence of excess adiposity and impaired skeletal muscle mass and function.
evidence level1
citationRusso C (2026)
sourceVitamin D and resveratrol in sarcopenic obesity: a systematic review highlighting the gap in phenotype-defined randomized controlled trials.
topicResveratrol Exercise Performance Randomized Trial
claimVitamin D and resveratrol modulate regulatory pathways implicated in SO pathophysiology, including NF-κB signaling, PGC-1α, mitochondrial regulation, and redox balance.
evidence level1
citationRusso C (2026)
sourceVitamin D and resveratrol in sarcopenic obesity: a systematic review highlighting the gap in phenotype-defined randomized controlled trials.
topicResveratrol Exercise Performance Randomized Trial
claimImportantly, these biological changes manifest most meaningfully through declines in functional capacity, including reduced muscle strength, impaired metabolic regulation, diminished cognitive performance, and increased disease risk.
evidence level4
citationKurtz Jennifer A. (2026)
sourceTargeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits
topicResveratrol Exercise Performance Randomized Trial
claimThis article aims to synthesize evidence from human studies evaluating dietary supplements that directly or indirectly modulate the recognized hallmarks of aging, such as mitochondrial dysfunction, oxidative stress, inflammation, and proteostasis.
evidence level4
citationKurtz Jennifer A. (2026)
sourceTargeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits
topicResveratrol Exercise Performance Randomized Trial
claimRather than providing an exhaustive account of all supplements ever studied, this review focuses on representative compounds with the strongest or most emerging human evidence.
evidence level4
citationKurtz Jennifer A. (2026)
sourceTargeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits
topicResveratrol Exercise Performance Randomized Trial
claimAging is a complex, multifaceted process marked by a gradual decline in physiological.
evidence level4
citationKurtz Jennifer A. (2026)
sourceTargeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits