topicResveratrol Cardiovascular Randomized Trial
claimThe main aim of this systematic review is to comprehensively evaluate and synthesize the current scientific evidence on the role of anthocyanins, curcumin, and resveratrol in the prevention and management of metabolic disorders, with a focus on obesity, type 2 diabetes, and dyslipidemia.
evidence level1
citationGazda P (2026)
sourceThe Role of Anthocyanins, Curcumin, and Resveratrol in the Prevention and Management of Metabolic Disorders: A Systematic Review.
topicResveratrol Cardiovascular Randomized Trial
claimThe analyzed studies demonstrated that anthocyanin supplementation (up to 320 mg/day) was associated with reductions in inflammatory markers such as IL-6 and TNF-α, improvements in HDL cholesterol, and modest reductions in HbA1c (~0.3-0.5%).
evidence level1
citationGazda P (2026)
sourceThe Role of Anthocyanins, Curcumin, and Resveratrol in the Prevention and Management of Metabolic Disorders: A Systematic Review.
topicResveratrol Cardiovascular Randomized Trial
claimCurcumin supplementation was associated with decreases in body weight (up to 0.82 kg), BMI (up to 0.30 kg/m 2 ), triglycerides, total cholesterol, and fasting glucose levels.
evidence level1
citationGazda P (2026)
sourceThe Role of Anthocyanins, Curcumin, and Resveratrol in the Prevention and Management of Metabolic Disorders: A Systematic Review.
topicResveratrol Cardiovascular Randomized Trial
claimMetabolic disorders such as obesity, type 2 diabetes, and lipid disorders are major health challenges worldwide.
evidence level1
citationGazda P (2026)
sourceThe Role of Anthocyanins, Curcumin, and Resveratrol in the Prevention and Management of Metabolic Disorders: A Systematic Review.
topicResveratrol Cardiovascular Randomized Trial
claimBackground and aims Menopause is an important cardiovascular risk factor in women likely due to marked estrogen decline.
evidence level2
citationGonçalinho GHF (2026)
sourceThe effects of resveratrol on endothelial progenitor cells and apoptosis biomarkers in postmenopausal women with chronic coronary heart disease: a randomized controlled trial.
topicResveratrol Cardiovascular Randomized Trial
claimConclusion Resveratrol increased serum Bcl-2 and cIAP2, and also reduced caspase 9 and circulating EPCs in postmenopausal women with chronic CHD, likely unrelated to circulating SIRT1 and SIRT3.
evidence level2
citationGonçalinho GHF (2026)
sourceThe effects of resveratrol on endothelial progenitor cells and apoptosis biomarkers in postmenopausal women with chronic coronary heart disease: a randomized controlled trial.
topicResveratrol Cardiovascular Randomized Trial
claimThe effects of resveratrol treatment in this population group should be assessed with caution, as a reduction in EPCs is associated with impaired endothelial function and an increased risk of cardiovascular disease.
evidence level2
citationGonçalinho GHF (2026)
sourceThe effects of resveratrol on endothelial progenitor cells and apoptosis biomarkers in postmenopausal women with chronic coronary heart disease: a randomized controlled trial.
topicResveratrol Cardiovascular Randomized Trial
claimEstrogens affect key processes in atherosclerosis, maintaining endothelial integrity by inhibiting endothelial apoptosis and promoting regeneration through endothelial progenitor cells (EPCs).
evidence level2
citationGonçalinho GHF (2026)
sourceThe effects of resveratrol on endothelial progenitor cells and apoptosis biomarkers in postmenopausal women with chronic coronary heart disease: a randomized controlled trial.