evidence table

Red Clover Menopause Randomized Trial Evidence Table

Structured evidence table for Red Clover Menopause Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Red Clover Menopause Randomized TrialBackground/Objectives : Interindividual variability in polyphenol metabolism may help explain the inconsistent effects of polyphenol intake on health outcomes.2Jarrín-Orozco MP (2025)Polyphenol-Related Gut Metabotype Signatures Linked to Quality of Life in Postmenopausal Women: A Randomized, Placebo-Controlled Crossover Trial.
Red Clover Menopause Randomized TrialThis study compared, for the first time, (i) polyphenol-related gut microbiota metabotypes (urolithins: UM0, UMA, UMB; equol: EP, ENP; lunularin: LP, LNP) and their clusters (MCs) in non-medicated premenopausal (Pre-M) and postmenopausal (Post-M) women and (ii) the impact of an 8-week intake of a polyphenol-rich plant extract mixture (PPs) on the quality of life (QoL) of Post-M.2Jarrín-Orozco MP (2025)Polyphenol-Related Gut Metabotype Signatures Linked to Quality of Life in Postmenopausal Women: A Randomized, Placebo-Controlled Crossover Trial.
Red Clover Menopause Randomized TrialAim To evaluate evidence supporting non-pharmacological interventions that modulate endogenous estrogen activity in postmenopausal women.4Bolgova O (2025)Natural strategies to optimize estrogen levels in aging women: mini review.
Red Clover Menopause Randomized TrialDietary phytoestrogens (50-80 mg/day isoflavones) reduced severe hot flashes by up to 92%, improved metabolic parameters, and were confirmed safe for reproductive tissues.4Bolgova O (2025)Natural strategies to optimize estrogen levels in aging women: mini review.
Red Clover Menopause Randomized TrialCurcumin (500 mg/day) reduced hot flashes after 4 weeks and improved metabolic profiles.4Bolgova O (2025)Natural strategies to optimize estrogen levels in aging women: mini review.
Red Clover Menopause Randomized TrialIntroduction Menopause triggers declining estradiol, causing vasomotor symptoms, bone loss, and urogenital changes.4Bolgova O (2025)Natural strategies to optimize estrogen levels in aging women: mini review.
topicRed Clover Menopause Randomized Trial
claimBackground/Objectives : Interindividual variability in polyphenol metabolism may help explain the inconsistent effects of polyphenol intake on health outcomes.
evidence level2
citationJarrín-Orozco MP (2025)
sourcePolyphenol-Related Gut Metabotype Signatures Linked to Quality of Life in Postmenopausal Women: A Randomized, Placebo-Controlled Crossover Trial.
topicRed Clover Menopause Randomized Trial
claimThis study compared, for the first time, (i) polyphenol-related gut microbiota metabotypes (urolithins: UM0, UMA, UMB; equol: EP, ENP; lunularin: LP, LNP) and their clusters (MCs) in non-medicated premenopausal (Pre-M) and postmenopausal (Post-M) women and (ii) the impact of an 8-week intake of a polyphenol-rich plant extract mixture (PPs) on the quality of life (QoL) of Post-M.
evidence level2
citationJarrín-Orozco MP (2025)
sourcePolyphenol-Related Gut Metabotype Signatures Linked to Quality of Life in Postmenopausal Women: A Randomized, Placebo-Controlled Crossover Trial.
topicRed Clover Menopause Randomized Trial
claimAim To evaluate evidence supporting non-pharmacological interventions that modulate endogenous estrogen activity in postmenopausal women.
evidence level4
citationBolgova O (2025)
sourceNatural strategies to optimize estrogen levels in aging women: mini review.
topicRed Clover Menopause Randomized Trial
claimDietary phytoestrogens (50-80 mg/day isoflavones) reduced severe hot flashes by up to 92%, improved metabolic parameters, and were confirmed safe for reproductive tissues.
evidence level4
citationBolgova O (2025)
sourceNatural strategies to optimize estrogen levels in aging women: mini review.
topicRed Clover Menopause Randomized Trial
claimCurcumin (500 mg/day) reduced hot flashes after 4 weeks and improved metabolic profiles.
evidence level4
citationBolgova O (2025)
sourceNatural strategies to optimize estrogen levels in aging women: mini review.
topicRed Clover Menopause Randomized Trial
claimIntroduction Menopause triggers declining estradiol, causing vasomotor symptoms, bone loss, and urogenital changes.
evidence level4
citationBolgova O (2025)
sourceNatural strategies to optimize estrogen levels in aging women: mini review.

Learn next

Related evidence and supplement guides

GuideRed Clover Menopause Randomized Trial: What the Evidence SaysRed Clover Menopause Randomized Trial has 2 source documents in the current Migaku evidence data...GuidePueraria Menopause Randomized Trial: What the Evidence SaysPueraria Menopause Randomized Trial has 2 source documents in the current Migaku evidence databa...GuideRed Clover Menopause Meta-analysis: What the Evidence SaysRed Clover Menopause Meta-analysis has 2 source documents in the current Migaku evidence databas...GuidePterostilbene Menopause Symptoms Randomized Trial: What the Evidence SaysPterostilbene Menopause Symptoms Randomized Trial has 2 source documents in the current Migaku e...AnswerDoes Pueraria Menopause Randomized Trial work?Pueraria Menopause Randomized Trial has evidence relevant to strength of evidence and what the s...AnswerIs Pueraria Menopause Randomized Trial safe?Pueraria Menopause Randomized Trial has evidence relevant to safety, limits, and clinician-discu...AnswerWhat does the evidence say about Pueraria Menopause Randomized Trial?Pueraria Menopause Randomized Trial has evidence relevant to benefits, uncertainty, and practica...AnswerDoes Riboflavin Fatigue Randomized Trial work?Riboflavin Fatigue Randomized Trial has evidence relevant to strength of evidence and what the s...

Source documents

  1. Polyphenol-Related Gut Metabotype Signatures Linked to Quality of Life in Postmenopausal Women: A Randomized, Placebo-Controlled Crossover Trial.
  2. Natural strategies to optimize estrogen levels in aging women: mini review.