Pycnogenol Skin Health Randomized Trial Evidence Table

Structured evidence table for Pycnogenol Skin Health Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Pycnogenol Skin Health Randomized TrialIts onset or worsening is associated with hormonal periods such as puberty, pregnancy, pregnancy induction, and menopause.2Mello Netto BAS (2025)Impact of Pycnogenol® Use in the Treatment of Patients With Lipedema: A Randomized Controlled Trial.
Pycnogenol Skin Health Randomized TrialAim Lipedema is a chronic, progressive disease that predominantly affects women and is strongly influenced by estrogen.2Mello Netto BAS (2025)Impact of Pycnogenol® Use in the Treatment of Patients With Lipedema: A Randomized Controlled Trial.
Pycnogenol Skin Health Randomized TrialFigure 1 Thus, in the present review we aimed to summarize the preclinical and clinical evidence of selected nutraceuticals, focusing on biotin, flavonoids especially luteolin, folic acid, Huperzine A, Lion’s mane, olive oil polyphenols (oleuropein and hydroxytyrosol [HT]), and palmitoylethanolamide (PEA).3Venetsanaki Vasiliki (2026)Natural Molecules for Brain Health and Resilience
Pycnogenol Skin Health Randomized TrialThe present narrative review highlights current mechanistic insights, as well as evidence from experimental and clinical studies regarding their potential roles in supporting cognitive function, modulating neuroinflammation, and mitigating neurodegenerative processes.3Venetsanaki Vasiliki (2026)Natural Molecules for Brain Health and Resilience
Pycnogenol Skin Health Randomized TrialIt should be noted that the present work consists of a review and not a dosing guideline.3Venetsanaki Vasiliki (2026)Natural Molecules for Brain Health and Resilience
Pycnogenol Skin Health Randomized Trial1 1 Brain health is a multidimensional and evolving concept that is difficult to evaluate and quantify [].3Venetsanaki Vasiliki (2026)Natural Molecules for Brain Health and Resilience
topicPycnogenol Skin Health Randomized Trial
claimIts onset or worsening is associated with hormonal periods such as puberty, pregnancy, pregnancy induction, and menopause.
evidence level2
citationMello Netto BAS (2025)
sourceImpact of Pycnogenol® Use in the Treatment of Patients With Lipedema: A Randomized Controlled Trial.
topicPycnogenol Skin Health Randomized Trial
claimAim Lipedema is a chronic, progressive disease that predominantly affects women and is strongly influenced by estrogen.
evidence level2
citationMello Netto BAS (2025)
sourceImpact of Pycnogenol® Use in the Treatment of Patients With Lipedema: A Randomized Controlled Trial.
topicPycnogenol Skin Health Randomized Trial
claimFigure 1 Thus, in the present review we aimed to summarize the preclinical and clinical evidence of selected nutraceuticals, focusing on biotin, flavonoids especially luteolin, folic acid, Huperzine A, Lion’s mane, olive oil polyphenols (oleuropein and hydroxytyrosol [HT]), and palmitoylethanolamide (PEA).
evidence level3
citationVenetsanaki Vasiliki (2026)
sourceNatural Molecules for Brain Health and Resilience
topicPycnogenol Skin Health Randomized Trial
claimThe present narrative review highlights current mechanistic insights, as well as evidence from experimental and clinical studies regarding their potential roles in supporting cognitive function, modulating neuroinflammation, and mitigating neurodegenerative processes.
evidence level3
citationVenetsanaki Vasiliki (2026)
sourceNatural Molecules for Brain Health and Resilience
topicPycnogenol Skin Health Randomized Trial
claimIt should be noted that the present work consists of a review and not a dosing guideline.
evidence level3
citationVenetsanaki Vasiliki (2026)
sourceNatural Molecules for Brain Health and Resilience
topicPycnogenol Skin Health Randomized Trial
claim1 1 Brain health is a multidimensional and evolving concept that is difficult to evaluate and quantify [].
evidence level3
citationVenetsanaki Vasiliki (2026)
sourceNatural Molecules for Brain Health and Resilience

Source documents

  1. Impact of Pycnogenol® Use in the Treatment of Patients With Lipedema: A Randomized Controlled Trial.
  2. Natural Molecules for Brain Health and Resilience