Structured evidence table for Pycnogenol Cognition Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Pycnogenol Cognition Randomized Trial | Methodological quality was assessed using the Cochrane Risk of Bias tool, and data were analyzed within a Bayesian framework. | 1 | Yang Y (2025) | Comparative efficacy and safety of botanical drugs for mild cognitive impairment: a systematic review and network meta-analysis. |
| Pycnogenol Cognition Randomized Trial | Conclusion Pycnogenol showed the highest probability of improving cognitive function and daily living scores in patients with MCI, while Cosmos caudatus supplementation ranked highest for psychological outcomes. | 1 | Yang Y (2025) | Comparative efficacy and safety of botanical drugs for mild cognitive impairment: a systematic review and network meta-analysis. |
| Pycnogenol Cognition Randomized Trial | Objective This study evaluated the comparative efficacy and safety of eighteen botanical drug interventions in improving cognitive function, daily living activities, and psychological wellbeing in patients with mild cognitive impairment (MCI). | 1 | Yang Y (2025) | Comparative efficacy and safety of botanical drugs for mild cognitive impairment: a systematic review and network meta-analysis. |
| Pycnogenol Cognition Randomized Trial | Methods Randomized controlled trials were identified from PubMed, Embase, Cochrane Library, and Web of Science up to September 2025. | 1 | Yang Y (2025) | Comparative efficacy and safety of botanical drugs for mild cognitive impairment: a systematic review and network meta-analysis. |
| Pycnogenol Cognition Randomized Trial | Figure 1 Thus, in the present review we aimed to summarize the preclinical and clinical evidence of selected nutraceuticals, focusing on biotin, flavonoids especially luteolin, folic acid, Huperzine A, Lion’s mane, olive oil polyphenols (oleuropein and hydroxytyrosol [HT]), and palmitoylethanolamide (PEA). | 3 | Venetsanaki Vasiliki (2026) | Natural Molecules for Brain Health and Resilience |
| Pycnogenol Cognition Randomized Trial | The present narrative review highlights current mechanistic insights, as well as evidence from experimental and clinical studies regarding their potential roles in supporting cognitive function, modulating neuroinflammation, and mitigating neurodegenerative processes. | 3 | Venetsanaki Vasiliki (2026) | Natural Molecules for Brain Health and Resilience |
| Pycnogenol Cognition Randomized Trial | It should be noted that the present work consists of a review and not a dosing guideline. | 3 | Venetsanaki Vasiliki (2026) | Natural Molecules for Brain Health and Resilience |
| Pycnogenol Cognition Randomized Trial | 1 1 Brain health is a multidimensional and evolving concept that is difficult to evaluate and quantify []. | 3 | Venetsanaki Vasiliki (2026) | Natural Molecules for Brain Health and Resilience |
Source documents