metabolic health

Pterostilbene Cardiometabolic Wellness Randomized Trial Evidence Table

Name: Pterostilbene Cardiometabolic Wellness Randomized Trial Evidence Table
Creator: Migaku

Structured evidence table for Pterostilbene Cardiometabolic Wellness Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topic	claim	evidence level	citation	source
Pterostilbene Cardiometabolic Wellness Randomized Trial	Cardiovascular disease, type 2 diabetes, cancer, neurodegenerative disorders, and other age-associated conditions (we have combined them into the term “multiple diseases”) share overlapping biological drivers, including oxidative stress, chronic low-grade inflammation, metabolic dysregulation, mitochondrial dysfunction, and cellular senescence.	3	Silverstein Harold Robert (2026)	The Simultaneous Prevention of Multiple Diseases: A “One Ring to Rule Them All” Framework for Redox-Driven Health and Longevity
Pterostilbene Cardiometabolic Wellness Randomized Trial	Rather than viewing these disorders as independent entities, increasing evidence supports a unified mechanistic perspective in which shared upstream processes give rise to diverse clinical outcomes.	3	Silverstein Harold Robert (2026)	The Simultaneous Prevention of Multiple Diseases: A “One Ring to Rule Them All” Framework for Redox-Driven Health and Longevity
Pterostilbene Cardiometabolic Wellness Randomized Trial	Attaining certain quantifiable health metrics has been associated with dramatic reductions in disease risk.	3	Silverstein Harold Robert (2026)	The Simultaneous Prevention of Multiple Diseases: A “One Ring to Rule Them All” Framework for Redox-Driven Health and Longevity
Pterostilbene Cardiometabolic Wellness Randomized Trial	Although cardiovascular disease remains a leading global cause of mortality [], it represents only one manifestation of a broader, systemic redox-inflammatory imbalance that contributes to multiple chronic pathologies.	3	Silverstein Harold Robert (2026)	The Simultaneous Prevention of Multiple Diseases: A “One Ring to Rule Them All” Framework for Redox-Driven Health and Longevity
Pterostilbene Cardiometabolic Wellness Randomized Trial	Mimio improved more over time in all hunger and satiety metrics than placebo (Hunger and Satiety Composite Score Mann-Kendall p = 2.2*10− 16).	4	Grant AD (2026)	A novel fasting mimetic (Mimio) creates fasting-like benefits to hunger control, oxidative stress, and cardiometabolic health in humans.
Pterostilbene Cardiometabolic Wellness Randomized Trial	More participants in the Mimio group improved daily ratings of hunger and appetite compared to placebo, including 91% vs.	4	Grant AD (2026)	A novel fasting mimetic (Mimio) creates fasting-like benefits to hunger control, oxidative stress, and cardiometabolic health in humans.
Pterostilbene Cardiometabolic Wellness Randomized Trial	Mimio significantly reduced total cholesterol, LDL cholesterol, LDL particle number, oxidized LDL, non-HDL cholesterol and fasting glucose compared to placebo (Student’s t-test p < 0.05).	4	Grant AD (2026)	A novel fasting mimetic (Mimio) creates fasting-like benefits to hunger control, oxidative stress, and cardiometabolic health in humans.
Pterostilbene Cardiometabolic Wellness Randomized Trial	This decentralized, double-blind, randomized, placebo-controlled trial investigated the impact of a novel fasting mimetic “Mimio” on hunger, satiety, digestive symptoms, metabolism, cognition and wellbeing in overweight older adults with elevated HbA1c.	4	Grant AD (2026)	A novel fasting mimetic (Mimio) creates fasting-like benefits to hunger control, oxidative stress, and cardiometabolic health in humans.