Pterostilbene Blood Pressure Randomized Trial Evidence Table

Structured evidence table for Pterostilbene Blood Pressure Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Pterostilbene Blood Pressure Randomized TrialReduced estradiol levels have been associated with undesirable symptoms of the menopause transition.2Holmes HE (2026)Nicotinamide riboside and pterostilbene reduces frequency and severity of undesirable symptoms of the menopause transition: an open-label, pilot clinical trial.
Pterostilbene Blood Pressure Randomized TrialAs anticipated NRPT intake significantly increased urinary levels of methyl-nicotinamide (Me-NAM) as well as the methylated pyridone carboxamides (Me-PYs) in all groups.2Holmes HE (2026)Nicotinamide riboside and pterostilbene reduces frequency and severity of undesirable symptoms of the menopause transition: an open-label, pilot clinical trial.
Pterostilbene Blood Pressure Randomized TrialIntroduction Nicotinamide adenine dinucleotide (NAD+) is a metabolite of vitamin B3 necessary for the production of key hormones like estradiol.2Holmes HE (2026)Nicotinamide riboside and pterostilbene reduces frequency and severity of undesirable symptoms of the menopause transition: an open-label, pilot clinical trial.
Pterostilbene Blood Pressure Randomized TrialProspective cohort studies and randomized controlled trials suggest that higher intakes of anthocyanin-rich foods are associated with improved vascular function, lower blood pressure, and reduced risk of coronary events and CVD [,,,,,,].3Jurja Sanda (2025)Blueberries and Honeysuckle Berries: Anthocyanin-Rich Polyphenols for Vascular Endothelial Health and Cardiovascular Disease Prevention
Pterostilbene Blood Pressure Randomized TrialClinical trials in various populations, ranging from healthy individuals to those with metabolic syndrome or elevated cardiometabolic risk, have reported improvements in surrogate markers of vascular health—including flow-mediated dilation (FMD), blood pressure, arterial stiffness, and circulating biomarkers of endothelial activation—after blueberry intake [,,,,,,,,,,,].3Jurja Sanda (2025)Blueberries and Honeysuckle Berries: Anthocyanin-Rich Polyphenols for Vascular Endothelial Health and Cardiovascular Disease Prevention
Pterostilbene Blood Pressure Randomized TrialNevertheless, not all studies have shown consistent benefits, and heterogeneity in dose, formulation, study duration, and population characteristics complicates the translation of these findings into clear, evidence-based dietary recommendations [,,,,,].3Jurja Sanda (2025)Blueberries and Honeysuckle Berries: Anthocyanin-Rich Polyphenols for Vascular Endothelial Health and Cardiovascular Disease Prevention
Pterostilbene Blood Pressure Randomized Trial1 2 3 4 5 6 7 8 9 10 10 11 12 Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality worldwide and is strongly driven by modifiable lifestyle factors, including diet, physical inactivity, smoking, and metabolic disorders such as hypertension, dyslipidemia, and type 2 diabetes [,,,,].3Jurja Sanda (2025)Blueberries and Honeysuckle Berries: Anthocyanin-Rich Polyphenols for Vascular Endothelial Health and Cardiovascular Disease Prevention
topicPterostilbene Blood Pressure Randomized Trial
claimReduced estradiol levels have been associated with undesirable symptoms of the menopause transition.
evidence level2
citationHolmes HE (2026)
sourceNicotinamide riboside and pterostilbene reduces frequency and severity of undesirable symptoms of the menopause transition: an open-label, pilot clinical trial.
topicPterostilbene Blood Pressure Randomized Trial
claimAs anticipated NRPT intake significantly increased urinary levels of methyl-nicotinamide (Me-NAM) as well as the methylated pyridone carboxamides (Me-PYs) in all groups.
evidence level2
citationHolmes HE (2026)
sourceNicotinamide riboside and pterostilbene reduces frequency and severity of undesirable symptoms of the menopause transition: an open-label, pilot clinical trial.
topicPterostilbene Blood Pressure Randomized Trial
claimIntroduction Nicotinamide adenine dinucleotide (NAD+) is a metabolite of vitamin B3 necessary for the production of key hormones like estradiol.
evidence level2
citationHolmes HE (2026)
sourceNicotinamide riboside and pterostilbene reduces frequency and severity of undesirable symptoms of the menopause transition: an open-label, pilot clinical trial.
topicPterostilbene Blood Pressure Randomized Trial
claimProspective cohort studies and randomized controlled trials suggest that higher intakes of anthocyanin-rich foods are associated with improved vascular function, lower blood pressure, and reduced risk of coronary events and CVD [,,,,,,].
evidence level3
citationJurja Sanda (2025)
sourceBlueberries and Honeysuckle Berries: Anthocyanin-Rich Polyphenols for Vascular Endothelial Health and Cardiovascular Disease Prevention
topicPterostilbene Blood Pressure Randomized Trial
claimClinical trials in various populations, ranging from healthy individuals to those with metabolic syndrome or elevated cardiometabolic risk, have reported improvements in surrogate markers of vascular health—including flow-mediated dilation (FMD), blood pressure, arterial stiffness, and circulating biomarkers of endothelial activation—after blueberry intake [,,,,,,,,,,,].
evidence level3
citationJurja Sanda (2025)
sourceBlueberries and Honeysuckle Berries: Anthocyanin-Rich Polyphenols for Vascular Endothelial Health and Cardiovascular Disease Prevention
topicPterostilbene Blood Pressure Randomized Trial
claimNevertheless, not all studies have shown consistent benefits, and heterogeneity in dose, formulation, study duration, and population characteristics complicates the translation of these findings into clear, evidence-based dietary recommendations [,,,,,].
evidence level3
citationJurja Sanda (2025)
sourceBlueberries and Honeysuckle Berries: Anthocyanin-Rich Polyphenols for Vascular Endothelial Health and Cardiovascular Disease Prevention
topicPterostilbene Blood Pressure Randomized Trial
claim1 2 3 4 5 6 7 8 9 10 10 11 12 Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality worldwide and is strongly driven by modifiable lifestyle factors, including diet, physical inactivity, smoking, and metabolic disorders such as hypertension, dyslipidemia, and type 2 diabetes [,,,,].
evidence level3
citationJurja Sanda (2025)
sourceBlueberries and Honeysuckle Berries: Anthocyanin-Rich Polyphenols for Vascular Endothelial Health and Cardiovascular Disease Prevention

Source documents

  1. Nicotinamide riboside and pterostilbene reduces frequency and severity of undesirable symptoms of the menopause transition: an open-label, pilot clinical trial.
  2. Blueberries and Honeysuckle Berries: Anthocyanin-Rich Polyphenols for Vascular Endothelial Health and Cardiovascular Disease Prevention