Structured evidence table for Prune Gut Microbiota Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Prune Gut Microbiota Randomized Trial | 1 2 3 4 7 Menopause is associated with a rapid decline in bone mineral density (BMD) and deterioration in bone quality, thus compromising bone strength and predisposing postmenopausal women to increased risk for osteoporosis and fragility fractures. | 4 | Simpson Abigayle M. R. (2024) | Gut microbes differ in postmenopausal women responding to prunes to maintain hip bone mineral density |
| Prune Gut Microbiota Randomized Trial | Calcium and vitamin D supplementation is considered a standard nutritional therapy for managing fracture risk (,). | 4 | Simpson Abigayle M. R. (2024) | Gut microbes differ in postmenopausal women responding to prunes to maintain hip bone mineral density |
| Prune Gut Microbiota Randomized Trial | There is increasing interest in leveraging select foods and bioactive food components for ameliorating bone loss and reducing fracture risk. | 4 | Simpson Abigayle M. R. (2024) | Gut microbes differ in postmenopausal women responding to prunes to maintain hip bone mineral density |
| Prune Gut Microbiota Randomized Trial | Dietary interventions are aimed at prevention of bone loss or as co-therapies to osteoporosis treatment. | 4 | Simpson Abigayle M. R. (2024) | Gut microbes differ in postmenopausal women responding to prunes to maintain hip bone mineral density |
| Prune Gut Microbiota Randomized Trial | Along with the striking effect on bone health, GC treatment and 25% DP supplementation led to drastic shifts in gut microbiota composition and several specific changes are strongly associated with bone health. | 4 | Chargo NJ (2024) | Glucocorticoid-induced osteoporosis is prevented by dietary prune in female mice. |
| Prune Gut Microbiota Randomized Trial | Glucocorticoid-induced osteoporosis (GIO) is a significant side effect of prolonged glucocorticoid (GC) treatment. | 4 | Chargo NJ (2024) | Glucocorticoid-induced osteoporosis is prevented by dietary prune in female mice. |
| Prune Gut Microbiota Randomized Trial | Chronic GC treatment also leads to trabecular bone loss and gut microbiota dysbiosis in mice. | 4 | Chargo NJ (2024) | Glucocorticoid-induced osteoporosis is prevented by dietary prune in female mice. |
Source documents