topicPropolis Skin Hydration Randomized Trial
claimAs a result, currently the cosmetic industry has significantly shifted toward natural and plant-based ingredients (–,) and The global essential oils market size in 2022 is expected to grow at a Compound Annual Growth Rate (CAGR) of 7.4% from 2023 to 2030 ().
evidence level1
citationPezantes-Orellana Camila (2025)
sourceEvaluating efficacy, safety, and innovation in skin care applications of essential oils: a systematic review
topicPropolis Skin Hydration Randomized Trial
claimMicroencapsulation has emerged as a key technology, allowing for the controlled release of essential oil components and improved stability (–).
evidence level1
citationPezantes-Orellana Camila (2025)
sourceEvaluating efficacy, safety, and innovation in skin care applications of essential oils: a systematic review
topicPropolis Skin Hydration Randomized Trial
claimThese technologies enhance the stability and efficacy of essential oils and allow for precise dosing, reducing the risk of skin irritation.
evidence level1
citationPezantes-Orellana Camila (2025)
sourceEvaluating efficacy, safety, and innovation in skin care applications of essential oils: a systematic review
topicPropolis Skin Hydration Randomized Trial
claim1 2 1 3 3 4 5 6 7 10 11 12 13 15 16 17 19 20 21 Essential oils (EOs) have gained significant traction in contemporary cosmetic products, offering natural alternatives to synthetic components ().
evidence level1
citationPezantes-Orellana Camila (2025)
sourceEvaluating efficacy, safety, and innovation in skin care applications of essential oils: a systematic review
topicPropolis Skin Hydration Randomized Trial
claimResults PRP and PRP-nano-propolis groups exhibited significantly decreased granulation tissue formation and enhanced collagen maturation compared to controls and lanolin-treated wounds (p Conclusions The application of nano-propolis and PRP, particularly in combination, significantly promotes cutaneous wound healing through enhanced antioxidant activity, and improved tissue repair mechanisms.
evidence level4
citationWafy MN (2026)
sourceNanostructured propolis ointment and platelet-rich plasma as novel biotherapeutics for cutaneous wound repair in an experimental canine model.
topicPropolis Skin Hydration Randomized Trial
claimBackground Effective management of cutaneous wounds is challenging in clinical practice.
evidence level4
citationWafy MN (2026)
sourceNanostructured propolis ointment and platelet-rich plasma as novel biotherapeutics for cutaneous wound repair in an experimental canine model.
topicPropolis Skin Hydration Randomized Trial
claimThe present study aimed to investigate the relative efficacy and explore the potential differences of nanostructured propolis ointment, platelet rich plasma (PRP) and their combination in enhancing the healing of experimentally induced cutaneous defect in dog model.
evidence level4
citationWafy MN (2026)
sourceNanostructured propolis ointment and platelet-rich plasma as novel biotherapeutics for cutaneous wound repair in an experimental canine model.