Structured evidence table for Probiotics Skin Health Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Probiotics Skin Health Randomized Trial | Standard therapy often relies on antibiotics, but the long-term use has increased antibiotic resistance, including in Indonesia. | 2 | Lestari K (2026) | Oral probiotics and topical secretome to enhance clinical outcomes and microbiome restoration in acne vulgaris: a double-blind, randomised controlled trial protocol. |
| Probiotics Skin Health Randomized Trial | Background Acne vulgaris is a chronic inflammatory condition primarily caused by Cutibacterium acnes , which disrupts skin homeostasis, thereby triggering immune responses and sebum metabolism. | 2 | Lestari K (2026) | Oral probiotics and topical secretome to enhance clinical outcomes and microbiome restoration in acne vulgaris: a double-blind, randomised controlled trial protocol. |
| Probiotics Skin Health Randomized Trial | Dysbiosis is an imbalance in the skin and gut microbiota identified as a significant factor contributing to acne progression. | 2 | Lestari K (2026) | Oral probiotics and topical secretome to enhance clinical outcomes and microbiome restoration in acne vulgaris: a double-blind, randomised controlled trial protocol. |
| Probiotics Skin Health Randomized Trial | Elevated reactive oxygen species (ROS) also play a key role, as increased ROS levels are found in patients with rosacea []. | 4 | Muacevic Alexander (2026) | The Role of Biotics in Rosacea: A Narrative Review |
| Probiotics Skin Health Randomized Trial | Mendelian randomization studies have linked certain bacterial taxa, including uncategorized[] andspecies [], to an increased risk of rosacea, while other taxa appear to confer a protective effect []. | 4 | Muacevic Alexander (2026) | The Role of Biotics in Rosacea: A Narrative Review |
| Probiotics Skin Health Randomized Trial | Although these studies provide limited mechanistic insight, they strengthen the evidence that microbial composition influences disease risk and expression. | 4 | Muacevic Alexander (2026) | The Role of Biotics in Rosacea: A Narrative Review |
| Probiotics Skin Health Randomized Trial | General features of rosacea 1 2 4 Rosacea is a chronic inflammatory skin condition affecting about 5.5% of adults, mainly aged 30-50. | 4 | Muacevic Alexander (2026) | The Role of Biotics in Rosacea: A Narrative Review |
Source documents