Structured evidence table for Probiotics and IBS, generated from 3 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Probiotics and IBS | As a result, the use of traditional treatment approaches, such as antispasmodics, microecological modulators, and cognitive behavioral interventions, is often limited in clinical practice owing to inadequate evidence to support their use and poor long-term adherence (). | 1 | Wu Jiali (2026) | Evaluation of the effectiveness of exercise therapy for irritable bowel syndrome: a systematic review and meta-analysis |
| Probiotics and IBS | Notably, neuromodulators like tricyclic antidepressants and serotonin–norepinephrine reuptake inhibitors are often associated with adverse effects, including nausea, vertigo, and sleep disturbances, which significantly impact adherence with treatment (). | 1 | Wu Jiali (2026) | Evaluation of the effectiveness of exercise therapy for irritable bowel syndrome: a systematic review and meta-analysis |
| Probiotics and IBS | We hope that through this analysis, we can not only validate the overall effects of exercise interventions but also provide direct evidence for developing personalized exercise prescriptions and promoting precision management of IBS. | 1 | Wu Jiali (2026) | Evaluation of the effectiveness of exercise therapy for irritable bowel syndrome: a systematic review and meta-analysis |
| Probiotics and IBS | Strengths Significant heterogeneity observed across studies (I = 84–92%). | 1 | Wu Jiali (2026) | Evaluation of the effectiveness of exercise therapy for irritable bowel syndrome: a systematic review and meta-analysis |
| Probiotics and IBS | This review summarizes the current concepts of probiotics and evaluates evidence supporting their use in patients with lower GI disorders, with a focus on potential sex-related differences. | 2 | Kim Yong Sung (2026) | Clinical Guidance and Practical Recommendations for Probiotic Use in Patients With Irritable Bowel Syndrome, Functional Constipation, and Clostridioides difficile Infection Considering Sex-based Differences |
| Probiotics and IBS | Saccharomyces, Lactobacillus Bifidobacterium Clostridium difficile 7 This review was conducted to summarize and interpret the current evidence on probiotics on IBS, FC, and CDI in terms of sex differences. | 2 | Kim Yong Sung (2026) | Clinical Guidance and Practical Recommendations for Probiotic Use in Patients With Irritable Bowel Syndrome, Functional Constipation, and Clostridioides difficile Infection Considering Sex-based Differences |
| Probiotics and IBS | Overall, probiotics significantly increased spontaneous bowel movement (SBM) per week by 0.67 (95% CI, 0.22-1.12) at 4 weeks after ingestion (). | 2 | Kim Yong Sung (2026) | Clinical Guidance and Practical Recommendations for Probiotic Use in Patients With Irritable Bowel Syndrome, Functional Constipation, and Clostridioides difficile Infection Considering Sex-based Differences |
| Probiotics and IBS | Clostridioides difficile 1 3 - 4 5 4 6 - For over a century, probiotics have been widely consumed as fermented beverages and supplements to promote gut health. | 2 | Kim Yong Sung (2026) | Clinical Guidance and Practical Recommendations for Probiotic Use in Patients With Irritable Bowel Syndrome, Functional Constipation, and Clostridioides difficile Infection Considering Sex-based Differences |
Source documents