topicProbiotic Skin Randomized Trial
claimAlthough some studies explored the effects of probiotic supplementation and physical activity as modulators, evidence remains limited.
evidence level1
citationRumão MS (2026)
sourceHuman Microbiome Alterations in Antarctic Isolated, Confined, and Extreme (ICE) Environments: A Systematic Review and Meta-Regression.
topicProbiotic Skin Randomized Trial
claimAntarctica is one of the most extreme and isolated environments on Earth, serving as a natural laboratory for studying human physiological and microbial adaptation under stress.
evidence level1
citationRumão MS (2026)
sourceHuman Microbiome Alterations in Antarctic Isolated, Confined, and Extreme (ICE) Environments: A Systematic Review and Meta-Regression.
topicProbiotic Skin Randomized Trial
claimThis systematic review and meta-regression evaluated how exposure to Antarctica's isolated, confined, and extreme (ICE) environments impacts the human microbiome, considering environmental and behavioral factors that may modulate these alterations.
evidence level1
citationRumão MS (2026)
sourceHuman Microbiome Alterations in Antarctic Isolated, Confined, and Extreme (ICE) Environments: A Systematic Review and Meta-Regression.
topicProbiotic Skin Randomized Trial
claimElevated reactive oxygen species (ROS) also play a key role, as increased ROS levels are found in patients with rosacea [].
evidence level4
citationMuacevic Alexander (2026)
sourceThe Role of Biotics in Rosacea: A Narrative Review
topicProbiotic Skin Randomized Trial
claimMendelian randomization studies have linked certain bacterial taxa, including uncategorized[] andspecies [], to an increased risk of rosacea, while other taxa appear to confer a protective effect [].
evidence level4
citationMuacevic Alexander (2026)
sourceThe Role of Biotics in Rosacea: A Narrative Review
topicProbiotic Skin Randomized Trial
claimAlthough these studies provide limited mechanistic insight, they strengthen the evidence that microbial composition influences disease risk and expression.
evidence level4
citationMuacevic Alexander (2026)
sourceThe Role of Biotics in Rosacea: A Narrative Review
topicProbiotic Skin Randomized Trial
claimGeneral features of rosacea 1 2 4 Rosacea is a chronic inflammatory skin condition affecting about 5.5% of adults, mainly aged 30-50.
evidence level4
citationMuacevic Alexander (2026)
sourceThe Role of Biotics in Rosacea: A Narrative Review