topicProbiotic Gut Barrier Randomized Trial
claimMoreover, an imbalanced gut microbiota is associated with the toxicity of anticancer therapies.
evidence level3
citationTao Mingyang (2026)
sourceThe role of the gut microbiota in radiation enteritis: from mechanistic insights to therapeutic applications
topicProbiotic Gut Barrier Randomized Trial
claimFor instance, the abundance ofandis correlated with increased chemotherapy toxicity in patients with lung cancer, while the abundance ofandis correlated with that in patients with gastrointestinal cancer.
evidence level3
citationTao Mingyang (2026)
sourceThe role of the gut microbiota in radiation enteritis: from mechanistic insights to therapeutic applications
topicProbiotic Gut Barrier Randomized Trial
claimThe abundance of., andis correlated with an increased risk of immune-related adverse events (irAEs) associated with immune checkpoint inhibitors (ICIs), whereas the abundance of.,andis associated with the opposite effect.
evidence level3
citationTao Mingyang (2026)
sourceThe role of the gut microbiota in radiation enteritis: from mechanistic insights to therapeutic applications
topicProbiotic Gut Barrier Randomized Trial
claim1 2 3 4 5 , 6 7 , 8 9 10 11 12 13 14 15 16 According to global cancer statistics, there were approximately 20 million new cancer cases and nearly 10 million cancer-related deaths worldwide in 2022.
evidence level3
citationTao Mingyang (2026)
sourceThe role of the gut microbiota in radiation enteritis: from mechanistic insights to therapeutic applications
topicProbiotic Gut Barrier Randomized Trial
claimAbout 1 in 100 children is born with a congenital heart defect, sometimes associated with genetic or chromosomal abnormalities such as Down syndrome.
evidence level4
citationLuca Alina-Costina (2026)
sourceThe Gut Microbiome in Congenital Heart Disease: Dysbiosis, Intestinal Barrier Injury, and Translational Opportunities Across the Childhood—A Narrative Review
topicProbiotic Gut Barrier Randomized Trial
claimRisk factors include heavy alcohol use during pregnancy, exposure to certain medications, and maternal viral infections in the first trimester.
evidence level4
citationLuca Alina-Costina (2026)
sourceThe Gut Microbiome in Congenital Heart Disease: Dysbiosis, Intestinal Barrier Injury, and Translational Opportunities Across the Childhood—A Narrative Review
topicProbiotic Gut Barrier Randomized Trial
claimIn addition, the risk is higher if a parent or sibling has congenital heart disease.
evidence level4
citationLuca Alina-Costina (2026)
sourceThe Gut Microbiome in Congenital Heart Disease: Dysbiosis, Intestinal Barrier Injury, and Translational Opportunities Across the Childhood—A Narrative Review
topicProbiotic Gut Barrier Randomized Trial
claim1 Congenital heart disease (CHD) refers to structural abnormalities of the heart that develop before birth.
evidence level4
citationLuca Alina-Costina (2026)
sourceThe Gut Microbiome in Congenital Heart Disease: Dysbiosis, Intestinal Barrier Injury, and Translational Opportunities Across the Childhood—A Narrative Review
topicProbiotic Gut Barrier Randomized Trial
claimElevated reactive oxygen species (ROS) also play a key role, as increased ROS levels are found in patients with rosacea [].
evidence level4
citationMuacevic Alexander (2026)
sourceThe Role of Biotics in Rosacea: A Narrative Review
topicProbiotic Gut Barrier Randomized Trial
claimMendelian randomization studies have linked certain bacterial taxa, including uncategorized[] andspecies [], to an increased risk of rosacea, while other taxa appear to confer a protective effect [].
evidence level4
citationMuacevic Alexander (2026)
sourceThe Role of Biotics in Rosacea: A Narrative Review
topicProbiotic Gut Barrier Randomized Trial
claimAlthough these studies provide limited mechanistic insight, they strengthen the evidence that microbial composition influences disease risk and expression.
evidence level4
citationMuacevic Alexander (2026)
sourceThe Role of Biotics in Rosacea: A Narrative Review
topicProbiotic Gut Barrier Randomized Trial
claimGeneral features of rosacea 1 2 4 Rosacea is a chronic inflammatory skin condition affecting about 5.5% of adults, mainly aged 30-50.
evidence level4
citationMuacevic Alexander (2026)
sourceThe Role of Biotics in Rosacea: A Narrative Review