Structured evidence table for Probiotic Digestive Comfort Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Probiotic Digestive Comfort Randomized Trial | Recently, alterations in gut microbiota composition have emerged as potential risk factors for the development of FC []. | 2 | Park Hyung Gyu (2026) | Effects of a spore-forming probiotic blend on bowel habits and physical well-being in adults with functional constipation: A randomized, double-blind, placebo-controlled trial |
| Probiotic Digestive Comfort Randomized Trial | Several studies have reported that gut microbiota dysbiosis—particularly a reduced abundance of,,, and—is associated with FC []. | 2 | Park Hyung Gyu (2026) | Effects of a spore-forming probiotic blend on bowel habits and physical well-being in adults with functional constipation: A randomized, double-blind, placebo-controlled trial |
| Probiotic Digestive Comfort Randomized Trial | Emerging evidence sup-ports the central role of gut microbiota in gastrointestinal homeostasis and highlights microbial balance as a critical factor in the effective management of FC []. | 2 | Park Hyung Gyu (2026) | Effects of a spore-forming probiotic blend on bowel habits and physical well-being in adults with functional constipation: A randomized, double-blind, placebo-controlled trial |
| Probiotic Digestive Comfort Randomized Trial | 1 2 4 5 6 7 Bifidobacteria Lactobacillus Bacteroides Prevotella Functional constipation (FC) is a common gastrointestinal disorder diagnosed based on the Rome IV criteria []. | 2 | Park Hyung Gyu (2026) | Effects of a spore-forming probiotic blend on bowel habits and physical well-being in adults with functional constipation: A randomized, double-blind, placebo-controlled trial |
| Probiotic Digestive Comfort Randomized Trial | The clinical impact is meaningful, as bloating and gas-related symptoms are associated with reduced quality-of-life and higher levels of stress and anxiety []. | 2 | Allegretti Jessica R. (2026) | A Randomized, Placebo-Controlled Trial Evaluating Multi-Species Synbiotic Supplementation for Bloating, Gas, and Abdominal Discomfort |
| Probiotic Digestive Comfort Randomized Trial | Clinically, disruption of GI barrier function is linked to increased sensitivity to visceral and somatic stimuli []. | 2 | Allegretti Jessica R. (2026) | A Randomized, Placebo-Controlled Trial Evaluating Multi-Species Synbiotic Supplementation for Bloating, Gas, and Abdominal Discomfort |
| Probiotic Digestive Comfort Randomized Trial | A trial of a single-strain probiotic (35624) over 4 weeks found no improvement in bloating or abdominal discomfort compared with placebo []. | 2 | Allegretti Jessica R. (2026) | A Randomized, Placebo-Controlled Trial Evaluating Multi-Species Synbiotic Supplementation for Bloating, Gas, and Abdominal Discomfort |
| Probiotic Digestive Comfort Randomized Trial | 1 2 2 3 3 Bloating and abdominal discomfort represent common clinical concerns in the general population. | 2 | Allegretti Jessica R. (2026) | A Randomized, Placebo-Controlled Trial Evaluating Multi-Species Synbiotic Supplementation for Bloating, Gas, and Abdominal Discomfort |
Source documents