evidence table
Probiotic Depression Randomized Trial Evidence Table
Structured evidence table for Probiotic Depression Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Probiotic Depression Randomized Trial | Anxiety is a prevalent non-motor symptom of Parkinson's disease (PD), yet treatment options remain limited. | 2 | Lam JST (2026) | Probiotic supplementation for anxiety symptoms in people with Parkinson's disease: a randomized, double-blind, placebo-controlled trial. |
| Probiotic Depression Randomized Trial | Both the probiotic (n = 30) and placebo (n = 31) groups showed significant within-group improvements on the Parkinson Anxiety Scale, with no significant between-group differences. | 2 | Lam JST (2026) | Probiotic supplementation for anxiety symptoms in people with Parkinson's disease: a randomized, double-blind, placebo-controlled trial. |
| Probiotic Depression Randomized Trial | 15 16 17 19 20 21 22 23 24 The emerging evidence supports that there is a bidirectional relationship between gut microbiota and depression, representing a paradigm shift in psychiatric research [,]. | 2 | Mosavat Seyed Hamdollah (2026) | Effect of probiotic supplement on improvement of depressive symptoms in patients with substance-induced depressive disorder: a randomized, double-blind, placebo-controlled clinical trial |
| Probiotic Depression Randomized Trial | Animal studies have presented some compelling evidence to suggest a causal role of dysbiosis in depression-like behaviours []. | 2 | Mosavat Seyed Hamdollah (2026) | Effect of probiotic supplement on improvement of depressive symptoms in patients with substance-induced depressive disorder: a randomized, double-blind, placebo-controlled clinical trial |
| Probiotic Depression Randomized Trial | MDD and SUD often co-occur, with each disorder increasing the risk of developing the other []. | 2 | Mosavat Seyed Hamdollah (2026) | Effect of probiotic supplement on improvement of depressive symptoms in patients with substance-induced depressive disorder: a randomized, double-blind, placebo-controlled clinical trial |
| Probiotic Depression Randomized Trial | 1 2 3 4 5 Major Depressive Disorder (MDD) is one of the most frequent and disabling psychiatric conditions worldwide, and recent estimates suggest that there are 300 million1 cases []. | 2 | Mosavat Seyed Hamdollah (2026) | Effect of probiotic supplement on improvement of depressive symptoms in patients with substance-induced depressive disorder: a randomized, double-blind, placebo-controlled clinical trial |
Source documents
- Probiotic supplementation for anxiety symptoms in people with Parkinson's disease: a randomized, double-blind, placebo-controlled trial.
- Effect of probiotic supplement on improvement of depressive symptoms in patients with substance-induced depressive disorder: a randomized, double-blind, placebo-controlled clinical trial