topicProbiotic Blood Lipids Randomized Trial
claimBackground Cardiovascular diseases, driven significantly by dyslipidemia, remain a leading global mortality risk.
evidence level1
citationZuo J (2025)
sourceEffect of Probiotics Containing <i>Lactobacillus plantarum</i> on Blood Lipids: Systematic Review, Meta-Analysis, and Network Pharmacological Analysis.
topicProbiotic Blood Lipids Randomized Trial
claimplantarum supplementation significantly reduced TC (SMD: -0.233; 95% CI: -0.458, -0.008; p = 0.042), TG (SMD: -0.227; 95% CI: -0.432, -0.021; p = 0.030), and LDL-C (SMD: -0.251; 95% CI: -0.477, -0.025; p = 0.029), but not HDL-C.
evidence level1
citationZuo J (2025)
sourceEffect of Probiotics Containing <i>Lactobacillus plantarum</i> on Blood Lipids: Systematic Review, Meta-Analysis, and Network Pharmacological Analysis.
topicProbiotic Blood Lipids Randomized Trial
claimplantarum ), which is a probiotic commonly used in a variety of food products, may contribute to the regulation of blood lipids, although prior studies report inconsistent efficacy and lack mechanistic clarity.
evidence level1
citationZuo J (2025)
sourceEffect of Probiotics Containing <i>Lactobacillus plantarum</i> on Blood Lipids: Systematic Review, Meta-Analysis, and Network Pharmacological Analysis.
topicProbiotic Blood Lipids Randomized Trial
claimBackground Emerging evidence suggests gut microbiota modulation may influence neurocognitive function through the gut-brain axis.
evidence level2
citationHuang J (2025)
sourceProbiotic supplementation on cognitive and other aging-related physiological functions in middle-aged and older adults with mild cognitive impairment (PCAMCI): protocol for a randomized, triple-blinded, placebo-controlled trial.
topicProbiotic Blood Lipids Randomized Trial
claimThe findings may inform the development of strategies to delay cognitive decline by modulating the gut-brain axis in this high-risk population.
evidence level2
citationHuang J (2025)
sourceProbiotic supplementation on cognitive and other aging-related physiological functions in middle-aged and older adults with mild cognitive impairment (PCAMCI): protocol for a randomized, triple-blinded, placebo-controlled trial.
topicProbiotic Blood Lipids Randomized Trial
claimAlthough preliminary studies indicate probiotics' potential benefits for mild cognitive impairment (MCI), well-designed randomized controlled trials remain limited.
evidence level2
citationHuang J (2025)
sourceProbiotic supplementation on cognitive and other aging-related physiological functions in middle-aged and older adults with mild cognitive impairment (PCAMCI): protocol for a randomized, triple-blinded, placebo-controlled trial.