sleep

Prebiotic Sleep Quality Randomized Trial Evidence Table

Structured evidence table for Prebiotic Sleep Quality Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Prebiotic Sleep Quality Randomized TrialThe clinical application of prebiotics has received increasing attention because of their low risk of serious side effects, ease of administration, and high potential to influence the composition and function of intestinal microbiota.2Tanihiro Reiko (2023)Effects of Prebiotic Yeast Mannan on Gut Health and Sleep Quality in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study
Prebiotic Sleep Quality Randomized TrialWe previously found that yeast mannan (YM) promotes the growth of specificin both in vitro and in vivo studies [,,].2Tanihiro Reiko (2023)Effects of Prebiotic Yeast Mannan on Gut Health and Sleep Quality in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study
Prebiotic Sleep Quality Randomized TrialAdditionally, YM intake promoted microbial equol production and improved skin dryness [].has attracted attention as a potential probiotic for the relief of Crohn’s disease [], but the effective use of increasinghas not yet been found in many areas.2Tanihiro Reiko (2023)Effects of Prebiotic Yeast Mannan on Gut Health and Sleep Quality in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study
Prebiotic Sleep Quality Randomized Trial1 2 3 4 5 6 7 8 9 10 10 11 12 7 8 13 9 9 14 Bacteroides Bacteroides thetaiotaomicron Ruminococcus Ruminococcaceae;g_ Clostridiales;f_;g_ B.2Tanihiro Reiko (2023)Effects of Prebiotic Yeast Mannan on Gut Health and Sleep Quality in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study
Prebiotic Sleep Quality Randomized TrialResults After 8 weeks, subjective insomnia scores and sleep onset and maintenance improved significantly, whereas the stress and mood disturbance scores decreased significantly.4Sasaki H (2025)Granola consumption with multiple prebiotics in Japanese participants increases <i>Bifidobacterium</i> abundance and improves stress and subjective sleepiness.
Prebiotic Sleep Quality Randomized TrialGut microbiota analysis showed that the relative abundance of Bifidobacterium increased, whereas that of Bacteroides decreased.4Sasaki H (2025)Granola consumption with multiple prebiotics in Japanese participants increases <i>Bifidobacterium</i> abundance and improves stress and subjective sleepiness.
Prebiotic Sleep Quality Randomized TrialCorrelation analysis suggested a significant association between increased Bifidobacterium level and reduced stress ( r = -0.39, p = 0.0035) and insomnia levels ( r = -0.3, p = 0.026).4Sasaki H (2025)Granola consumption with multiple prebiotics in Japanese participants increases <i>Bifidobacterium</i> abundance and improves stress and subjective sleepiness.
Prebiotic Sleep Quality Randomized TrialHowever, stress-related sleep disorders are common in Japan, and the gut-brain axis may play a role in sleep and stress management.4Sasaki H (2025)Granola consumption with multiple prebiotics in Japanese participants increases <i>Bifidobacterium</i> abundance and improves stress and subjective sleepiness.
topicPrebiotic Sleep Quality Randomized Trial
claimThe clinical application of prebiotics has received increasing attention because of their low risk of serious side effects, ease of administration, and high potential to influence the composition and function of intestinal microbiota.
evidence level2
citationTanihiro Reiko (2023)
sourceEffects of Prebiotic Yeast Mannan on Gut Health and Sleep Quality in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study
topicPrebiotic Sleep Quality Randomized Trial
claimWe previously found that yeast mannan (YM) promotes the growth of specificin both in vitro and in vivo studies [,,].
evidence level2
citationTanihiro Reiko (2023)
sourceEffects of Prebiotic Yeast Mannan on Gut Health and Sleep Quality in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study
topicPrebiotic Sleep Quality Randomized Trial
claimAdditionally, YM intake promoted microbial equol production and improved skin dryness [].has attracted attention as a potential probiotic for the relief of Crohn’s disease [], but the effective use of increasinghas not yet been found in many areas.
evidence level2
citationTanihiro Reiko (2023)
sourceEffects of Prebiotic Yeast Mannan on Gut Health and Sleep Quality in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study
topicPrebiotic Sleep Quality Randomized Trial
claim1 2 3 4 5 6 7 8 9 10 10 11 12 7 8 13 9 9 14 Bacteroides Bacteroides thetaiotaomicron Ruminococcus Ruminococcaceae;g_ Clostridiales;f_;g_ B.
evidence level2
citationTanihiro Reiko (2023)
sourceEffects of Prebiotic Yeast Mannan on Gut Health and Sleep Quality in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study
topicPrebiotic Sleep Quality Randomized Trial
claimResults After 8 weeks, subjective insomnia scores and sleep onset and maintenance improved significantly, whereas the stress and mood disturbance scores decreased significantly.
evidence level4
citationSasaki H (2025)
sourceGranola consumption with multiple prebiotics in Japanese participants increases <i>Bifidobacterium</i> abundance and improves stress and subjective sleepiness.
topicPrebiotic Sleep Quality Randomized Trial
claimGut microbiota analysis showed that the relative abundance of Bifidobacterium increased, whereas that of Bacteroides decreased.
evidence level4
citationSasaki H (2025)
sourceGranola consumption with multiple prebiotics in Japanese participants increases <i>Bifidobacterium</i> abundance and improves stress and subjective sleepiness.
topicPrebiotic Sleep Quality Randomized Trial
claimCorrelation analysis suggested a significant association between increased Bifidobacterium level and reduced stress ( r = -0.39, p = 0.0035) and insomnia levels ( r = -0.3, p = 0.026).
evidence level4
citationSasaki H (2025)
sourceGranola consumption with multiple prebiotics in Japanese participants increases <i>Bifidobacterium</i> abundance and improves stress and subjective sleepiness.
topicPrebiotic Sleep Quality Randomized Trial
claimHowever, stress-related sleep disorders are common in Japan, and the gut-brain axis may play a role in sleep and stress management.
evidence level4
citationSasaki H (2025)
sourceGranola consumption with multiple prebiotics in Japanese participants increases <i>Bifidobacterium</i> abundance and improves stress and subjective sleepiness.

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Source documents

  1. Effects of Prebiotic Yeast Mannan on Gut Health and Sleep Quality in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study
  2. Granola consumption with multiple prebiotics in Japanese participants increases <i>Bifidobacterium</i> abundance and improves stress and subjective sleepiness.