evidence table

Prebiotic Skin Health Randomized Trial Evidence Table

Structured evidence table for Prebiotic Skin Health Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Prebiotic Skin Health Randomized TrialIt is postulated that, apart from genetic predisposition, the rise of local and systemic immune response in PS could be a consequence of intestinal dysbiosis associated with increased intestinal permeability.2Krupa-Kozak U (2026)INulin-type β-fructans supplementation to modulate gut microbiota and assessment of its effects on health status and GUT-SKIN axis parameters in patients with psoriasis (INGUTSKIN): the 8-week, randomised, double-blind, placebo-controlled clinical study protocol.
Prebiotic Skin Health Randomized TrialWe expect that the RCT results will enable the introduction of personalised dietary therapy with prebiotic ITFs, which, unlike other PS therapies, would not pose a high risk of side effects.2Krupa-Kozak U (2026)INulin-type β-fructans supplementation to modulate gut microbiota and assessment of its effects on health status and GUT-SKIN axis parameters in patients with psoriasis (INGUTSKIN): the 8-week, randomised, double-blind, placebo-controlled clinical study protocol.
Prebiotic Skin Health Randomized TrialBACKGROUND: A strong, bidirectional association exists between gastrointestinal health and skin homeostasis in many chronic skin inflammations, including psoriasis (PS).2Krupa-Kozak U (2026)INulin-type β-fructans supplementation to modulate gut microbiota and assessment of its effects on health status and GUT-SKIN axis parameters in patients with psoriasis (INGUTSKIN): the 8-week, randomised, double-blind, placebo-controlled clinical study protocol.
Prebiotic Skin Health Randomized Trialobjective Theof this paper is to analyze the available scientific evidence on the cutaneous microbiome and its relationship with skin health.4Taléns‐Visconti Raquel (2026)Cosmetic Interventions for Skin Microbiome Modulation: Current Strategies and Future Directions
Prebiotic Skin Health Randomized Trialacnes 14 15 16 2 15 12 12 2 3 3 17 18 19 13 15 16 The skin microbiome shifts notably throughout life, from the low diversity observed in newborns, to the emergence of lipophilic species with puberty, and typically an increase in overall alpha diversity in older adults due to reduced dominance of protective commensals such asand, coupled with higher representation of environmental/transient species [,].4Taléns‐Visconti Raquel (2026)Cosmetic Interventions for Skin Microbiome Modulation: Current Strategies and Future Directions
Prebiotic Skin Health Randomized TrialA study found that women exhibit higher alpha diversity than men, indicating a richer and more balanced microbiota [].4Taléns‐Visconti Raquel (2026)Cosmetic Interventions for Skin Microbiome Modulation: Current Strategies and Future Directions
Prebiotic Skin Health Randomized Trial1 Human skin, owing to its large surface area, plays a key role as the primary point of direct contact with the environment.4Taléns‐Visconti Raquel (2026)Cosmetic Interventions for Skin Microbiome Modulation: Current Strategies and Future Directions
topicPrebiotic Skin Health Randomized Trial
claimIt is postulated that, apart from genetic predisposition, the rise of local and systemic immune response in PS could be a consequence of intestinal dysbiosis associated with increased intestinal permeability.
evidence level2
citationKrupa-Kozak U (2026)
sourceINulin-type β-fructans supplementation to modulate gut microbiota and assessment of its effects on health status and GUT-SKIN axis parameters in patients with psoriasis (INGUTSKIN): the 8-week, randomised, double-blind, placebo-controlled clinical study protocol.
topicPrebiotic Skin Health Randomized Trial
claimWe expect that the RCT results will enable the introduction of personalised dietary therapy with prebiotic ITFs, which, unlike other PS therapies, would not pose a high risk of side effects.
evidence level2
citationKrupa-Kozak U (2026)
sourceINulin-type β-fructans supplementation to modulate gut microbiota and assessment of its effects on health status and GUT-SKIN axis parameters in patients with psoriasis (INGUTSKIN): the 8-week, randomised, double-blind, placebo-controlled clinical study protocol.
topicPrebiotic Skin Health Randomized Trial
claimBACKGROUND: A strong, bidirectional association exists between gastrointestinal health and skin homeostasis in many chronic skin inflammations, including psoriasis (PS).
evidence level2
citationKrupa-Kozak U (2026)
sourceINulin-type β-fructans supplementation to modulate gut microbiota and assessment of its effects on health status and GUT-SKIN axis parameters in patients with psoriasis (INGUTSKIN): the 8-week, randomised, double-blind, placebo-controlled clinical study protocol.
topicPrebiotic Skin Health Randomized Trial
claimobjective Theof this paper is to analyze the available scientific evidence on the cutaneous microbiome and its relationship with skin health.
evidence level4
citationTaléns‐Visconti Raquel (2026)
sourceCosmetic Interventions for Skin Microbiome Modulation: Current Strategies and Future Directions
topicPrebiotic Skin Health Randomized Trial
claimacnes 14 15 16 2 15 12 12 2 3 3 17 18 19 13 15 16 The skin microbiome shifts notably throughout life, from the low diversity observed in newborns, to the emergence of lipophilic species with puberty, and typically an increase in overall alpha diversity in older adults due to reduced dominance of protective commensals such asand, coupled with higher representation of environmental/transient species [,].
evidence level4
citationTaléns‐Visconti Raquel (2026)
sourceCosmetic Interventions for Skin Microbiome Modulation: Current Strategies and Future Directions
topicPrebiotic Skin Health Randomized Trial
claimA study found that women exhibit higher alpha diversity than men, indicating a richer and more balanced microbiota [].
evidence level4
citationTaléns‐Visconti Raquel (2026)
sourceCosmetic Interventions for Skin Microbiome Modulation: Current Strategies and Future Directions
topicPrebiotic Skin Health Randomized Trial
claim1 Human skin, owing to its large surface area, plays a key role as the primary point of direct contact with the environment.
evidence level4
citationTaléns‐Visconti Raquel (2026)
sourceCosmetic Interventions for Skin Microbiome Modulation: Current Strategies and Future Directions

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Source documents

  1. INulin-type β-fructans supplementation to modulate gut microbiota and assessment of its effects on health status and GUT-SKIN axis parameters in patients with psoriasis (INGUTSKIN): the 8-week, randomised, double-blind, placebo-controlled clinical study protocol.
  2. Cosmetic Interventions for Skin Microbiome Modulation: Current Strategies and Future Directions