topicPrebiotic Inulin Constipation Randomized Trial
claimAs a result, total IBS-QoL score increased in the prebiotic group (61.0 ± 19.4 to 77.4 ± 15.1; p group×time ), psychological state (7 (2-10) to 9 (5-10); p < 0.006).
evidence level2
citationAkçalı Ç (2025)
sourceA randomized trial of inulin for bowel symptoms, depression and quality of life in constipation predominant IBS.
topicPrebiotic Inulin Constipation Randomized Trial
claimThis study was conducted to evaluate the effect of inulin on bowel symptoms, depression and quality of life in individuals with constipation-predominant irritable bowel syndrome.
evidence level2
citationAkçalı Ç (2025)
sourceA randomized trial of inulin for bowel symptoms, depression and quality of life in constipation predominant IBS.
topicPrebiotic Inulin Constipation Randomized Trial
claimThis study was designed as a randomized, single-blind, placebo-controlled clinical trial with a parallel design and a 1:1 allocation ratio.
evidence level2
citationAkçalı Ç (2025)
sourceA randomized trial of inulin for bowel symptoms, depression and quality of life in constipation predominant IBS.
topicPrebiotic Inulin Constipation Randomized Trial
claimThis, in turn, can lead to a more diverse and resilient gut microbiota, which is associated with positive health outcomes.
evidence level3
citationMonteiro Cinara Regina A. V. (2026)
sourcePrebiotics and Gut Health: Mechanisms, Clinical Evidence, and Future Directions
topicPrebiotic Inulin Constipation Randomized Trial
claimCurrent literature often lacks an integrative analysis that bridges mechanistic insights rooted in prebiotic structure and function with heterogeneous clinical evidence derived from human trials.
evidence level3
citationMonteiro Cinara Regina A. V. (2026)
sourcePrebiotics and Gut Health: Mechanisms, Clinical Evidence, and Future Directions
topicPrebiotic Inulin Constipation Randomized Trial
claimAccording to the International Scientific Association for Probiotics and Prebiotics (ISAPP), a prebiotic is defined as “a substrate that is selectively utilized by host microorganisms conferring a health benefit.” This definition highlights two key characteristics: selective utilization by beneficial microorganisms and evidence of physiological benefits to the host [].
evidence level3
citationMonteiro Cinara Regina A. V. (2026)
sourcePrebiotics and Gut Health: Mechanisms, Clinical Evidence, and Future Directions
topicPrebiotic Inulin Constipation Randomized Trial
claim1 2 3 2 3 4 5 6 7 8 Gut health is a critical factor in overall well-being and plays a pivotal role in maintaining optimal physiological function [,,].
evidence level3
citationMonteiro Cinara Regina A. V. (2026)
sourcePrebiotics and Gut Health: Mechanisms, Clinical Evidence, and Future Directions