topicPrebiotic Dental Plaque Randomized Trial
claimAIM: This systematic review and meta-analysis aimed to compare the effectiveness of probiotics, prebiotics, synbiotics, and postbiotics in preventing dental caries and to assess associated microbiological and ecological outcomes.
evidence level1
citationLu C (2026)
sourceComparative effectiveness of probiotics, prebiotics, synbiotics, and postbiotics in preventing dental caries: a meta-analysis from an oral microbiota modulation perspective.
topicPrebiotic Dental Plaque Randomized Trial
claimData extraction and risk-of-bias assessments were conducted independently by two reviewers.
evidence level1
citationLu C (2026)
sourceComparative effectiveness of probiotics, prebiotics, synbiotics, and postbiotics in preventing dental caries: a meta-analysis from an oral microbiota modulation perspective.
topicPrebiotic Dental Plaque Randomized Trial
claimRandom-effects meta-analysis was applied to estimate pooled risk ratios (RRs) with subgroup analyses by age, strain, delivery format, and duration.
evidence level1
citationLu C (2026)
sourceComparative effectiveness of probiotics, prebiotics, synbiotics, and postbiotics in preventing dental caries: a meta-analysis from an oral microbiota modulation perspective.
topicPrebiotic Dental Plaque Randomized Trial
claimBACKGROUND: Dental caries remains one of the most prevalent non-communicable diseases worldwide, imposing substantial health and economic burdens despite conventional preventive measures such as fluoride use and oral hygiene.
evidence level1
citationLu C (2026)
sourceComparative effectiveness of probiotics, prebiotics, synbiotics, and postbiotics in preventing dental caries: a meta-analysis from an oral microbiota modulation perspective.