topicPrebiotic Bloating Randomized Trial
claimProbiotics can alleviate some gastrointestinal (GI) symptoms; however, evidence for their impact on bloating, gas and abdominal discomfort in otherwise healthy populations remains limited.
evidence level2
citationAllegretti JR (2026)
sourceA Randomized, Placebo-Controlled Trial Evaluating Multi-Species Synbiotic Supplementation for Bloating, Gas, and Abdominal Discomfort.
topicPrebiotic Bloating Randomized Trial
claimMechanistic studies suggest that synbiotics may influence the underlying mechanisms of bloating, including increased gas production, impaired gut motility, and visceral hypersensitivity, but there is a paucity of data from large trials evaluating clinical outcomes.
evidence level2
citationAllegretti JR (2026)
sourceA Randomized, Placebo-Controlled Trial Evaluating Multi-Species Synbiotic Supplementation for Bloating, Gas, and Abdominal Discomfort.
topicPrebiotic Bloating Randomized Trial
claimResults : The multi-species synbiotic improved GI quality-of-life compared to placebo (0.80 vs.
evidence level2
citationAllegretti JR (2026)
sourceA Randomized, Placebo-Controlled Trial Evaluating Multi-Species Synbiotic Supplementation for Bloating, Gas, and Abdominal Discomfort.
topicPrebiotic Bloating Randomized Trial
claimBackground: Bloating, gas, and abdominal discomfort are common in healthy individuals but lack effective interventions.
evidence level2
citationAllegretti JR (2026)
sourceA Randomized, Placebo-Controlled Trial Evaluating Multi-Species Synbiotic Supplementation for Bloating, Gas, and Abdominal Discomfort.