Structured evidence table for Pqq Fatigue Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Pqq Fatigue Randomized Trial | During exercise, various internal changes such as increased heart and respiratory rates, muscle pain, and emotional fluctuations are transmitted to the central nervous system. | 2 | Zhao Chenxi (2026) | The effects of pyrroloquinoline quinone and nicotinamide mononucleotide supplementation on interoception following acute exhaustive exercise: a randomised, double-blind, placebo-controlled study |
| Pqq Fatigue Randomized Trial | This process, referred to as “exercise interoception”, is enhanced by exercise via stimulated visceral signals, increased peripheral sensitivity, and improved neural plasticity. | 2 | Zhao Chenxi (2026) | The effects of pyrroloquinoline quinone and nicotinamide mononucleotide supplementation on interoception following acute exhaustive exercise: a randomised, double-blind, placebo-controlled study |
| Pqq Fatigue Randomized Trial | Evidence suggests that fasting or nutritional supplements can influence cardiac interoception by modulating autonomic nervous system activity and neuro-related mechanisms, indicating a potential relationship between nutritional interventions and interoception. | 2 | Zhao Chenxi (2026) | The effects of pyrroloquinoline quinone and nicotinamide mononucleotide supplementation on interoception following acute exhaustive exercise: a randomised, double-blind, placebo-controlled study |
| Pqq Fatigue Randomized Trial | 1 2 3 4 , 5 3 Interoception, defined as the nervous system’s capacity to sense, interpret, and integrate signals originating from within the body, is crucial for adaptive responses to physiological changes. | 2 | Zhao Chenxi (2026) | The effects of pyrroloquinoline quinone and nicotinamide mononucleotide supplementation on interoception following acute exhaustive exercise: a randomised, double-blind, placebo-controlled study |
| Pqq Fatigue Randomized Trial | While obesity is known to be associated with health risks such as hypertension and diabetes in the general population, it confers additional risks to both mother and fetus during pregnancy. | 4 | Castillo-Castrejon Marisol (2026) | A role for the antioxidants coenzyme Q10 and pyrroloquinoline quinone in mitigating obesity-associated reproductive dysfunction † |
| Pqq Fatigue Randomized Trial | Risks of obesity in early pregnancy include increased risk of miscarriage [] as well as fetal anomalies, including neural tube defects, cardiac anomalies, oral facial clefts, and limb reduction anomalies []. | 4 | Castillo-Castrejon Marisol (2026) | A role for the antioxidants coenzyme Q10 and pyrroloquinoline quinone in mitigating obesity-associated reproductive dysfunction † |
| Pqq Fatigue Randomized Trial | Maternal conditions associated with obesity in pregnancy include increased incidence of preeclampsia (PE), gestational diabetes, and cesarean delivery []. | 4 | Castillo-Castrejon Marisol (2026) | A role for the antioxidants coenzyme Q10 and pyrroloquinoline quinone in mitigating obesity-associated reproductive dysfunction † |
| Pqq Fatigue Randomized Trial | 1 2 3 4 4 5 6 The prevalence of obesity continues to rise in the United States and is now considered a non-communicable disease epidemic by the U.S. | 4 | Castillo-Castrejon Marisol (2026) | A role for the antioxidants coenzyme Q10 and pyrroloquinoline quinone in mitigating obesity-associated reproductive dysfunction † |
Source documents