evidence table

Pomegranate Seed Oil Endothelial Function Randomized Trial Evidence Table

Structured evidence table for Pomegranate Seed Oil Endothelial Function Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Pomegranate Seed Oil Endothelial Function Randomized TrialHormonal changes associated with this stage of life contribute to a higher CVD risk, driven by factors such as visceral obesity, atherogenic dyslipidemia, vascular dysfunction, and high blood pressure (BP).2Almoraie Manal M (2026)Acute Effects of a High-Fat Meal Enriched with Pomegranate Seed Oil on Postprandial Lipemia and Endothelial Function in Postmenopausal Women: a Randomized Controlled Crossover Trial
Pomegranate Seed Oil Endothelial Function Randomized TrialHowever, a direct association between menopause and increased risk of CVD events has only been confirmed in cases of early (premature) menopause [,].2Almoraie Manal M (2026)Acute Effects of a High-Fat Meal Enriched with Pomegranate Seed Oil on Postprandial Lipemia and Endothelial Function in Postmenopausal Women: a Randomized Controlled Crossover Trial
Pomegranate Seed Oil Endothelial Function Randomized TrialNon-fasting triacylglycerol (TAG) concentrations are an independent, modifiable CVD risk factor [,], and considered more discriminatory of risk than fasting concentrations in women [,,].2Almoraie Manal M (2026)Acute Effects of a High-Fat Meal Enriched with Pomegranate Seed Oil on Postprandial Lipemia and Endothelial Function in Postmenopausal Women: a Randomized Controlled Crossover Trial
Pomegranate Seed Oil Endothelial Function Randomized Trial1 1 2 3 4 [5] [6] [7] [8] [9] [10] 4 8 11 12 13 11 14 15 [16] [17] [18] 19 Cardiovascular diseases (CVD) are a significant concern in females transitioning to menopause [].2Almoraie Manal M (2026)Acute Effects of a High-Fat Meal Enriched with Pomegranate Seed Oil on Postprandial Lipemia and Endothelial Function in Postmenopausal Women: a Randomized Controlled Crossover Trial
Pomegranate Seed Oil Endothelial Function Randomized TrialPSO significantly reduced histological injury: Median total injury score was 9 (7-11) in IR, 6 (4-8) in IR + PSO low, and 3 (2-5) in IR + PSO high ( P < 0.001).4Altimimi MLM (2026)Effects of pomegranate seed oil on lower-extremity ischemia-reperfusion damage: Insights into oxidative stress, inflammation, and cell death.
Pomegranate Seed Oil Endothelial Function Randomized TrialMultivariable logistic regression showed that PSO treatment was associated with lower odds of severe IR injury (odds ratio: 0.40, 95% confidence interval: 0.18-0.90).4Altimimi MLM (2026)Effects of pomegranate seed oil on lower-extremity ischemia-reperfusion damage: Insights into oxidative stress, inflammation, and cell death.
Pomegranate Seed Oil Endothelial Function Randomized TrialIn this exploratory study, PSO supplementation was associated with reduced histological and biochemical markers of IR injury, with greater effects at higher dose.4Altimimi MLM (2026)Effects of pomegranate seed oil on lower-extremity ischemia-reperfusion damage: Insights into oxidative stress, inflammation, and cell death.
Pomegranate Seed Oil Endothelial Function Randomized TrialLower-extremity ischemia-reperfusion (IR) injury causes oxidative stress, inflammation, and cell death.4Altimimi MLM (2026)Effects of pomegranate seed oil on lower-extremity ischemia-reperfusion damage: Insights into oxidative stress, inflammation, and cell death.
topicPomegranate Seed Oil Endothelial Function Randomized Trial
claimHormonal changes associated with this stage of life contribute to a higher CVD risk, driven by factors such as visceral obesity, atherogenic dyslipidemia, vascular dysfunction, and high blood pressure (BP).
evidence level2
citationAlmoraie Manal M (2026)
sourceAcute Effects of a High-Fat Meal Enriched with Pomegranate Seed Oil on Postprandial Lipemia and Endothelial Function in Postmenopausal Women: a Randomized Controlled Crossover Trial
topicPomegranate Seed Oil Endothelial Function Randomized Trial
claimHowever, a direct association between menopause and increased risk of CVD events has only been confirmed in cases of early (premature) menopause [,].
evidence level2
citationAlmoraie Manal M (2026)
sourceAcute Effects of a High-Fat Meal Enriched with Pomegranate Seed Oil on Postprandial Lipemia and Endothelial Function in Postmenopausal Women: a Randomized Controlled Crossover Trial
topicPomegranate Seed Oil Endothelial Function Randomized Trial
claimNon-fasting triacylglycerol (TAG) concentrations are an independent, modifiable CVD risk factor [,], and considered more discriminatory of risk than fasting concentrations in women [,,].
evidence level2
citationAlmoraie Manal M (2026)
sourceAcute Effects of a High-Fat Meal Enriched with Pomegranate Seed Oil on Postprandial Lipemia and Endothelial Function in Postmenopausal Women: a Randomized Controlled Crossover Trial
topicPomegranate Seed Oil Endothelial Function Randomized Trial
claim1 1 2 3 4 [5] [6] [7] [8] [9] [10] 4 8 11 12 13 11 14 15 [16] [17] [18] 19 Cardiovascular diseases (CVD) are a significant concern in females transitioning to menopause [].
evidence level2
citationAlmoraie Manal M (2026)
sourceAcute Effects of a High-Fat Meal Enriched with Pomegranate Seed Oil on Postprandial Lipemia and Endothelial Function in Postmenopausal Women: a Randomized Controlled Crossover Trial
topicPomegranate Seed Oil Endothelial Function Randomized Trial
claimPSO significantly reduced histological injury: Median total injury score was 9 (7-11) in IR, 6 (4-8) in IR + PSO low, and 3 (2-5) in IR + PSO high ( P < 0.001).
evidence level4
citationAltimimi MLM (2026)
sourceEffects of pomegranate seed oil on lower-extremity ischemia-reperfusion damage: Insights into oxidative stress, inflammation, and cell death.
topicPomegranate Seed Oil Endothelial Function Randomized Trial
claimMultivariable logistic regression showed that PSO treatment was associated with lower odds of severe IR injury (odds ratio: 0.40, 95% confidence interval: 0.18-0.90).
evidence level4
citationAltimimi MLM (2026)
sourceEffects of pomegranate seed oil on lower-extremity ischemia-reperfusion damage: Insights into oxidative stress, inflammation, and cell death.
topicPomegranate Seed Oil Endothelial Function Randomized Trial
claimIn this exploratory study, PSO supplementation was associated with reduced histological and biochemical markers of IR injury, with greater effects at higher dose.
evidence level4
citationAltimimi MLM (2026)
sourceEffects of pomegranate seed oil on lower-extremity ischemia-reperfusion damage: Insights into oxidative stress, inflammation, and cell death.
topicPomegranate Seed Oil Endothelial Function Randomized Trial
claimLower-extremity ischemia-reperfusion (IR) injury causes oxidative stress, inflammation, and cell death.
evidence level4
citationAltimimi MLM (2026)
sourceEffects of pomegranate seed oil on lower-extremity ischemia-reperfusion damage: Insights into oxidative stress, inflammation, and cell death.

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Source documents

  1. Acute Effects of a High-Fat Meal Enriched with Pomegranate Seed Oil on Postprandial Lipemia and Endothelial Function in Postmenopausal Women: a Randomized Controlled Crossover Trial
  2. Effects of pomegranate seed oil on lower-extremity ischemia-reperfusion damage: Insights into oxidative stress, inflammation, and cell death.