Structured evidence table for Polydextrose Gut Health Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Polydextrose Gut Health Randomized Trial | Results Both synbiotic yogurts increased levels of beneficial organic acids, such as propionate and lactate, and decreased ammonium ion concentrations, indicating a shift toward saccharolytic fermentation. | 4 | Pessotti RC (2025) | Polydextrose-driven gut microbiota modulation from synbiotic yogurt intake simulated in the <i>in vitro</i> dynamic multivessel colonic xGI<i>biomics</i> system. |
| Polydextrose Gut Health Randomized Trial | The synbiotic formulation incorporating polydextrose also led to increased butyrate production when compared to the yogurt containing only the BB-12 ® probiotic, and a greater relative abundance of Bifidobacterium spp. | 4 | Pessotti RC (2025) | Polydextrose-driven gut microbiota modulation from synbiotic yogurt intake simulated in the <i>in vitro</i> dynamic multivessel colonic xGI<i>biomics</i> system. |
| Polydextrose Gut Health Randomized Trial | Additionally, both synbiotic treatments reduced Klebsiella spp., a potentially pathogenic genus. | 4 | Pessotti RC (2025) | Polydextrose-driven gut microbiota modulation from synbiotic yogurt intake simulated in the <i>in vitro</i> dynamic multivessel colonic xGI<i>biomics</i> system. |
| Polydextrose Gut Health Randomized Trial | Introduction The gut microbiota plays a pivotal role in maintaining host health and dietary strategies, such as synbiotic interventions, have emerged as promising tools to modulate its composition and metabolic activity. | 4 | Pessotti RC (2025) | Polydextrose-driven gut microbiota modulation from synbiotic yogurt intake simulated in the <i>in vitro</i> dynamic multivessel colonic xGI<i>biomics</i> system. |
| Polydextrose Gut Health Randomized Trial | In addition, consuming dietary prebiotics reduced the neutrophil-to-lymphocyte ratio (NLR) and increased red blood cell distribution width (RDW-CV). | 4 | Thompson RS (2025) | A Prebiotic Diet Containing Galactooligosaccharides and Polydextrose Attenuates Hypergravity-Induced Disruptions to the Microbiome in Female Mice. |
| Polydextrose Gut Health Randomized Trial | Furthermore, several prebiotic diet-induced genera-level changes were significantly associated with several host physiological changes induced by 3g exposure. | 4 | Thompson RS (2025) | A Prebiotic Diet Containing Galactooligosaccharides and Polydextrose Attenuates Hypergravity-Induced Disruptions to the Microbiome in Female Mice. |
| Polydextrose Gut Health Randomized Trial | Background/objectives Environmental stressors, including spaceflight and altered gravity, can negatively affect the symbiotic relationship between the gut microbiome and host health. | 4 | Thompson RS (2025) | A Prebiotic Diet Containing Galactooligosaccharides and Polydextrose Attenuates Hypergravity-Induced Disruptions to the Microbiome in Female Mice. |
| Polydextrose Gut Health Randomized Trial | Dietary prebiotics, which alter components of the gut microbiome, show promise as an effective way to mitigate the negative impacts of stressor exposure. | 4 | Thompson RS (2025) | A Prebiotic Diet Containing Galactooligosaccharides and Polydextrose Attenuates Hypergravity-Induced Disruptions to the Microbiome in Female Mice. |
Source documents