topicPine Bark Supplementation Blood Pressure Randomized Trial
claimBackground Supplementation with pine bark extract (PBE) may improve risk factors associated with cardiometabolic syndrome (CMS).
evidence level1
citationMohammadi S (2025)
sourceDoes supplementation with pine bark extract improve cardiometabolic risk factors? A systematic review and meta-analysis.
topicPine Bark Supplementation Blood Pressure Randomized Trial
claimThe effects of PBE supplementation on cardiometabolic risk factors were evaluated in this systematic review and meta-analysis of randomized controlled trials (RCTs).
evidence level1
citationMohammadi S (2025)
sourceDoes supplementation with pine bark extract improve cardiometabolic risk factors? A systematic review and meta-analysis.
topicPine Bark Supplementation Blood Pressure Randomized Trial
claimAs population aging accelerates, identifying modifiable risk factors and preventive strategies for cognitive decline has become increasingly important.
evidence level2
citationHsiao Tse-Chia (2026)
sourceCombined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study
topicPine Bark Supplementation Blood Pressure Randomized Trial
claim4 5 5 6 7 8 9 10 11 10 Mild cognitive impairment (MCI) represents an intermediate stage between normal cognitive function and dementia [], and individuals with MCI have a significantly higher risk of progressing to dementia than cognitively normal individuals [].
evidence level2
citationHsiao Tse-Chia (2026)
sourceCombined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study
topicPine Bark Supplementation Blood Pressure Randomized Trial
claimLifestyle-related factors, including suboptimal dietary patterns, smoking, alcohol use, obesity, and physical inactivity, have been identified as modifiable risk factors for cognitive decline [].
evidence level2
citationHsiao Tse-Chia (2026)
sourceCombined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study
topicPine Bark Supplementation Blood Pressure Randomized Trial
claim1 2 3 Dementia is a major global health concern and a leading cause of disability and dependency among older adults worldwide [].
evidence level2
citationHsiao Tse-Chia (2026)
sourceCombined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study