Pine Bark Memory Randomized Trial Evidence Table

Structured evidence table for Pine Bark Memory Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Pine Bark Memory Randomized TrialThese findings suggest that combined supplementation with fish oil and pine bark extract may be associated with potential improvements in short-term memory performance and antioxidant status in middle-aged and older adults with MCI, although the results should be interpreted cautiously.2Hsiao TC (2026)Combined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study.
Pine Bark Memory Randomized TrialMild cognitive impairment (MCI) represents an intermediate stage between normal cognitive function and dementia.2Hsiao TC (2026)Combined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study.
Pine Bark Memory Randomized TrialDelaying the onset or progression of dementia has therefore become a key research priority.2Hsiao TC (2026)Combined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study.
Pine Bark Memory Randomized TrialFigure 1 Thus, in the present review we aimed to summarize the preclinical and clinical evidence of selected nutraceuticals, focusing on biotin, flavonoids especially luteolin, folic acid, Huperzine A, Lion’s mane, olive oil polyphenols (oleuropein and hydroxytyrosol [HT]), and palmitoylethanolamide (PEA).3Venetsanaki Vasiliki (2026)Natural Molecules for Brain Health and Resilience
Pine Bark Memory Randomized TrialThe present narrative review highlights current mechanistic insights, as well as evidence from experimental and clinical studies regarding their potential roles in supporting cognitive function, modulating neuroinflammation, and mitigating neurodegenerative processes.3Venetsanaki Vasiliki (2026)Natural Molecules for Brain Health and Resilience
Pine Bark Memory Randomized TrialIt should be noted that the present work consists of a review and not a dosing guideline.3Venetsanaki Vasiliki (2026)Natural Molecules for Brain Health and Resilience
Pine Bark Memory Randomized Trial1 1 Brain health is a multidimensional and evolving concept that is difficult to evaluate and quantify [].3Venetsanaki Vasiliki (2026)Natural Molecules for Brain Health and Resilience
topicPine Bark Memory Randomized Trial
claimThese findings suggest that combined supplementation with fish oil and pine bark extract may be associated with potential improvements in short-term memory performance and antioxidant status in middle-aged and older adults with MCI, although the results should be interpreted cautiously.
evidence level2
citationHsiao TC (2026)
sourceCombined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study.
topicPine Bark Memory Randomized Trial
claimMild cognitive impairment (MCI) represents an intermediate stage between normal cognitive function and dementia.
evidence level2
citationHsiao TC (2026)
sourceCombined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study.
topicPine Bark Memory Randomized Trial
claimDelaying the onset or progression of dementia has therefore become a key research priority.
evidence level2
citationHsiao TC (2026)
sourceCombined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study.
topicPine Bark Memory Randomized Trial
claimFigure 1 Thus, in the present review we aimed to summarize the preclinical and clinical evidence of selected nutraceuticals, focusing on biotin, flavonoids especially luteolin, folic acid, Huperzine A, Lion’s mane, olive oil polyphenols (oleuropein and hydroxytyrosol [HT]), and palmitoylethanolamide (PEA).
evidence level3
citationVenetsanaki Vasiliki (2026)
sourceNatural Molecules for Brain Health and Resilience
topicPine Bark Memory Randomized Trial
claimThe present narrative review highlights current mechanistic insights, as well as evidence from experimental and clinical studies regarding their potential roles in supporting cognitive function, modulating neuroinflammation, and mitigating neurodegenerative processes.
evidence level3
citationVenetsanaki Vasiliki (2026)
sourceNatural Molecules for Brain Health and Resilience
topicPine Bark Memory Randomized Trial
claimIt should be noted that the present work consists of a review and not a dosing guideline.
evidence level3
citationVenetsanaki Vasiliki (2026)
sourceNatural Molecules for Brain Health and Resilience
topicPine Bark Memory Randomized Trial
claim1 1 Brain health is a multidimensional and evolving concept that is difficult to evaluate and quantify [].
evidence level3
citationVenetsanaki Vasiliki (2026)
sourceNatural Molecules for Brain Health and Resilience

Source documents

  1. Combined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study.
  2. Natural Molecules for Brain Health and Resilience