topicPine Bark Extract Blood Pressure Randomized Trial
claimSeveral factors contribute to CMS-associated complications, including genetics, nutrition, epigenetics, lifestyle choices, and environmental factors [,].
evidence level1
citationMohammadi Shooka (2025)
sourceDoes supplementation with pine bark extract improve cardiometabolic risk factors? A systematic review and meta-analysis
topicPine Bark Extract Blood Pressure Randomized Trial
claim11 12 11 13 14 11 15 12 16 17 Various pathological procedures are associated with diverse clinical manifestations of CMS [,].
evidence level1
citationMohammadi Shooka (2025)
sourceDoes supplementation with pine bark extract improve cardiometabolic risk factors? A systematic review and meta-analysis
topicPine Bark Extract Blood Pressure Randomized Trial
claimIn addition, CMS is associated with increased OS and inflammatory marker levels [].
evidence level1
citationMohammadi Shooka (2025)
sourceDoes supplementation with pine bark extract improve cardiometabolic risk factors? A systematic review and meta-analysis
topicPine Bark Extract Blood Pressure Randomized Trial
claim1 2 3 4 5 6 7 9 7 10 Cardiometabolic syndrome (CMS), also known as metabolic syndrome (MetS) or insulin resistance syndrome, includes several metabolic dysfunctions [].
evidence level1
citationMohammadi Shooka (2025)
sourceDoes supplementation with pine bark extract improve cardiometabolic risk factors? A systematic review and meta-analysis
topicPine Bark Extract Blood Pressure Randomized Trial
claimet Zucc.) bark is a by-product of the wood industry and contains a high level of antioxidative phenolics including flavonoids, which have a variety of beneficial health effects.
evidence level4
citationKim KJ (2020)
sourceAntihypertensive Effects of Polyphenolic Extract from Korean Red Pine (<i>Pinus densiflora</i> Sieb. et Zucc.) Bark in Spontaneously Hypertensive Rats.
topicPine Bark Extract Blood Pressure Randomized Trial
claimdensiflora bark extract (Korean red pine bark extract; KRPBE) in spontaneously hypertensive rats (SHRs).
evidence level4
citationKim KJ (2020)
sourceAntihypertensive Effects of Polyphenolic Extract from Korean Red Pine (<i>Pinus densiflora</i> Sieb. et Zucc.) Bark in Spontaneously Hypertensive Rats.