Structured evidence table for Pine Bark Cognitive Performance Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Pine Bark Cognitive Performance Randomized Trial | As population aging accelerates, identifying modifiable risk factors and preventive strategies for cognitive decline has become increasingly important. | 2 | Hsiao Tse-Chia (2026) | Combined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study |
| Pine Bark Cognitive Performance Randomized Trial | 4 5 5 6 7 8 9 10 11 10 Mild cognitive impairment (MCI) represents an intermediate stage between normal cognitive function and dementia [], and individuals with MCI have a significantly higher risk of progressing to dementia than cognitively normal individuals []. | 2 | Hsiao Tse-Chia (2026) | Combined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study |
| Pine Bark Cognitive Performance Randomized Trial | Lifestyle-related factors, including suboptimal dietary patterns, smoking, alcohol use, obesity, and physical inactivity, have been identified as modifiable risk factors for cognitive decline []. | 2 | Hsiao Tse-Chia (2026) | Combined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study |
| Pine Bark Cognitive Performance Randomized Trial | 1 2 3 Dementia is a major global health concern and a leading cause of disability and dependency among older adults worldwide []. | 2 | Hsiao Tse-Chia (2026) | Combined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study |
| Pine Bark Cognitive Performance Randomized Trial | Figure 1 Thus, in the present review we aimed to summarize the preclinical and clinical evidence of selected nutraceuticals, focusing on biotin, flavonoids especially luteolin, folic acid, Huperzine A, Lion’s mane, olive oil polyphenols (oleuropein and hydroxytyrosol [HT]), and palmitoylethanolamide (PEA). | 3 | Venetsanaki Vasiliki (2026) | Natural Molecules for Brain Health and Resilience |
| Pine Bark Cognitive Performance Randomized Trial | The present narrative review highlights current mechanistic insights, as well as evidence from experimental and clinical studies regarding their potential roles in supporting cognitive function, modulating neuroinflammation, and mitigating neurodegenerative processes. | 3 | Venetsanaki Vasiliki (2026) | Natural Molecules for Brain Health and Resilience |
| Pine Bark Cognitive Performance Randomized Trial | It should be noted that the present work consists of a review and not a dosing guideline. | 3 | Venetsanaki Vasiliki (2026) | Natural Molecules for Brain Health and Resilience |
| Pine Bark Cognitive Performance Randomized Trial | 1 1 Brain health is a multidimensional and evolving concept that is difficult to evaluate and quantify []. | 3 | Venetsanaki Vasiliki (2026) | Natural Molecules for Brain Health and Resilience |
Source documents