Pine Bark Cognition Randomized Trial Evidence Table

Structured evidence table for Pine Bark Cognition Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Pine Bark Cognition Randomized TrialThese findings suggest that combined supplementation with fish oil and pine bark extract may be associated with potential improvements in short-term memory performance and antioxidant status in middle-aged and older adults with MCI, although the results should be interpreted cautiously.2Hsiao TC (2026)Combined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study.
Pine Bark Cognition Randomized TrialMild cognitive impairment (MCI) represents an intermediate stage between normal cognitive function and dementia.2Hsiao TC (2026)Combined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study.
Pine Bark Cognition Randomized TrialDelaying the onset or progression of dementia has therefore become a key research priority.2Hsiao TC (2026)Combined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study.
Pine Bark Cognition Randomized TrialIn parallel, epidemiological evidence has consistently linked specific dietary patterns, such as the Mediterranean and MIND diets, to a reduced risk of cognitive decline and AD [].2Kumari Ankita (2026)Dietary Bioactives in Alzheimer’s Disease: A Critical Appraisal of Clinical Trials and Future Nutritional Strategies
Pine Bark Cognition Randomized TrialThese changes progress to reduced brain volume and are responsible for the memory loss associated with AD [].2Kumari Ankita (2026)Dietary Bioactives in Alzheimer’s Disease: A Critical Appraisal of Clinical Trials and Future Nutritional Strategies
Pine Bark Cognition Randomized TrialThis definition aligns with the Office of Dietary Supplements (NIH, Bethesda, MD, USA) framework, which characterizes bioactives as food or supplement constituents, excluding essential nutrients that influence cellular activities, metabolic pathways, or disease risk [].2Kumari Ankita (2026)Dietary Bioactives in Alzheimer’s Disease: A Critical Appraisal of Clinical Trials and Future Nutritional Strategies
Pine Bark Cognition Randomized Trial1 2 The prevalence of Alzheimer’s disease (AD) is projected to escalate in line with rising life expectancies across various nations.2Kumari Ankita (2026)Dietary Bioactives in Alzheimer’s Disease: A Critical Appraisal of Clinical Trials and Future Nutritional Strategies
topicPine Bark Cognition Randomized Trial
claimThese findings suggest that combined supplementation with fish oil and pine bark extract may be associated with potential improvements in short-term memory performance and antioxidant status in middle-aged and older adults with MCI, although the results should be interpreted cautiously.
evidence level2
citationHsiao TC (2026)
sourceCombined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study.
topicPine Bark Cognition Randomized Trial
claimMild cognitive impairment (MCI) represents an intermediate stage between normal cognitive function and dementia.
evidence level2
citationHsiao TC (2026)
sourceCombined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study.
topicPine Bark Cognition Randomized Trial
claimDelaying the onset or progression of dementia has therefore become a key research priority.
evidence level2
citationHsiao TC (2026)
sourceCombined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study.
topicPine Bark Cognition Randomized Trial
claimIn parallel, epidemiological evidence has consistently linked specific dietary patterns, such as the Mediterranean and MIND diets, to a reduced risk of cognitive decline and AD [].
evidence level2
citationKumari Ankita (2026)
sourceDietary Bioactives in Alzheimer’s Disease: A Critical Appraisal of Clinical Trials and Future Nutritional Strategies
topicPine Bark Cognition Randomized Trial
claimThese changes progress to reduced brain volume and are responsible for the memory loss associated with AD [].
evidence level2
citationKumari Ankita (2026)
sourceDietary Bioactives in Alzheimer’s Disease: A Critical Appraisal of Clinical Trials and Future Nutritional Strategies
topicPine Bark Cognition Randomized Trial
claimThis definition aligns with the Office of Dietary Supplements (NIH, Bethesda, MD, USA) framework, which characterizes bioactives as food or supplement constituents, excluding essential nutrients that influence cellular activities, metabolic pathways, or disease risk [].
evidence level2
citationKumari Ankita (2026)
sourceDietary Bioactives in Alzheimer’s Disease: A Critical Appraisal of Clinical Trials and Future Nutritional Strategies
topicPine Bark Cognition Randomized Trial
claim1 2 The prevalence of Alzheimer’s disease (AD) is projected to escalate in line with rising life expectancies across various nations.
evidence level2
citationKumari Ankita (2026)
sourceDietary Bioactives in Alzheimer’s Disease: A Critical Appraisal of Clinical Trials and Future Nutritional Strategies

Source documents

  1. Combined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study.
  2. Dietary Bioactives in Alzheimer’s Disease: A Critical Appraisal of Clinical Trials and Future Nutritional Strategies