Structured evidence table for Phosphorus Bone Health Meta-Analysis, generated from 3 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Phosphorus Bone Health Meta-Analysis | The prevalence rate in people over 65 years old increased to 32.0%, and that of women was as high as 51.6% []. | 3 | Osman Henigul (2026) | Research Progress on Mechanisms of Milk-Derived Functional Components in Regulating Bone Health and the Gut–Bone Axis |
| Phosphorus Bone Health Meta-Analysis | Further studies have shown that the absolute burden of osteoporosis in menopausal women continues to increase, with the highest risk in low-and middle-income countries and women over 85 years of age []. | 3 | Osman Henigul (2026) | Research Progress on Mechanisms of Milk-Derived Functional Components in Regulating Bone Health and the Gut–Bone Axis |
| Phosphorus Bone Health Meta-Analysis | These drugs have the characteristics of high cost-effectiveness and medicinal value, convenient use, effective improvement of bone mineral density, and reduction of fracture risk. | 3 | Osman Henigul (2026) | Research Progress on Mechanisms of Milk-Derived Functional Components in Regulating Bone Health and the Gut–Bone Axis |
| Phosphorus Bone Health Meta-Analysis | 1 2 3 Bone serves as the fundamental structural framework that maintains the integrity of the organism and supports motor function, and its metabolic homeostasis depends on a delicate and tightly regulated balance between bone formation mediated by osteoblasts and bone resorption mediated by osteoclasts []. | 3 | Osman Henigul (2026) | Research Progress on Mechanisms of Milk-Derived Functional Components in Regulating Bone Health and the Gut–Bone Axis |
| Phosphorus Bone Health Meta-Analysis | Calcium and vitamin D are well-established for maintaining bone mass and reducing fracture risk, particularly in deficient or high-risk populations, whereas evidence supporting the roles of vitamin K, magnesium, and phosphorus is more limited and population specific. | 3 | da Silva Tiago Donizeti Bertolacini (2025) | Supplements for bone health |
| Phosphorus Bone Health Meta-Analysis | 1 2 3 This review has three primary objectives: () to delineate the physiological functions of calcium, vitamin D, vitamin K, magnesium, and phosphorus in bone metabolism; () to summarize current dietary intake recommendations and evaluate the Brazilian context; () to synthesize evidence from meta-analyses and systematic reviews regarding their impact on bone health. | 3 | da Silva Tiago Donizeti Bertolacini (2025) | Supplements for bone health |
| Phosphorus Bone Health Meta-Analysis | Conversely, elevated serum calcium levels suppress PTH secretion through negative feedback, leading to decreased bone resorption and reduced calcium reabsorption in the kidneys (,). | 3 | da Silva Tiago Donizeti Bertolacini (2025) | Supplements for bone health |
| Phosphorus Bone Health Meta-Analysis | Bone health is determined by a complex interplay of genetic, hormonal, and environmental factors, with nutrient intake representing an important contributor to skeletal integrity. | 3 | da Silva Tiago Donizeti Bertolacini (2025) | Supplements for bone health |
| Phosphorus Bone Health Meta-Analysis | Specifically, we evaluated the following factors: (1) adequate sequence generation, (2) allocation concealment, (3) blinding, and (4) intention-to-treat analysis; each question was rated as “high risk,” “low risk,” or “unclear,” with 2 reviewers (W.H. | 4 | Hou Wenping (2026) | Comparative Effectiveness and Safety of Phosphorus-Lowering Drugs for CKD 3-5 Stages |
| Phosphorus Bone Health Meta-Analysis | Finally, the percentages associated with each possible rank were computed for all interventions. | 4 | Hou Wenping (2026) | Comparative Effectiveness and Safety of Phosphorus-Lowering Drugs for CKD 3-5 Stages |
| Phosphorus Bone Health Meta-Analysis | Figs S1 S2 Table S2 Using the Cochrane Collaboration tool, we assessed the risk of bias across studies, which was frequently found to be high (and). | 4 | Hou Wenping (2026) | Comparative Effectiveness and Safety of Phosphorus-Lowering Drugs for CKD 3-5 Stages |
| Phosphorus Bone Health Meta-Analysis | Although calcium-based phosphate binders exhibit consistent therapeutic efficacy and cost-effectiveness, their prolonged use may lead to an elevated calcium burden,thereby potentially resulting in hypercalcemiaand vascular calcification, among other complications.In recent years, advancements in new drug research and development have led to the development of various types of phosphorus-lowering drugs. | 4 | Hou Wenping (2026) | Comparative Effectiveness and Safety of Phosphorus-Lowering Drugs for CKD 3-5 Stages |
Source documents