topicPhosphatidylserine Stress Randomized Trial
claimFailure to meet the recommended 7-9 hours of restful sleep per night is known to increase the risk of several health conditions, reason why regular and adequate sleep should be seen as a priority instead of an unnecessary commodity easily traded as required by the commitments of our busy lives.
evidence level4
citationConti F (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review.
topicPhosphatidylserine Stress Randomized Trial
claimWhile both the quantity and the quality of sleep can be largely improved with relatively straightforward practices dictated by good sleep hygiene, emerging research suggests that dietary and supplementation protocols focused on certain foods, nutrients, and biochemical compounds with sleep-promoting properties can act as subsidiary sleep aids in complementing these behavioral changes.
evidence level4
citationConti F (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review.
topicPhosphatidylserine Stress Randomized Trial
claimThe scope of this narrative review is to summarize the available evidence on the potential benefits of selected nutraceuticals in the context of circadian rhythm and sleep disturbances, namely melatonin, magnesium, omega-3 fatty acids, tart cherry juice, kiwifruit, apigenin, valerian root, L-theanine, glycine, ashwagandha, myoinositol, Rhodiola rosea, and phosphatidylserine.
evidence level4
citationConti F (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review.
topicPhosphatidylserine Stress Randomized Trial
claimHumans spend approximately one third of their life asleep but, as counterintuitive as it may sound, sleep is far from being a quiet state of inactivity.
evidence level4
citationConti F (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review.
topicPhosphatidylserine Stress Randomized Trial
claimGiven the lack of disease-modifying therapies for dementia, interventions that can stabilize or improve cognition at the MCI stage may substantially reduce future dementia incidence and associated healthcare costs.
evidence level4
citationOh Kang-Il (2026)
sourceNeuroprotective Effect of the Combined Extract of Mentha piperita and Cornus officinalis Against Neuronal Cell Death and Scopolamine-Induced Memory Impairment
topicPhosphatidylserine Stress Randomized Trial
claimBecause reduced BDNF signaling is closely linked to synaptic dysfunction and memory decline in MCI, we measured BDNF expression in both in vitro and in vivo experiments and assessed downstream ERK/AKT/CREB signaling in the in vivo model.
evidence level4
citationOh Kang-Il (2026)
sourceNeuroprotective Effect of the Combined Extract of Mentha piperita and Cornus officinalis Against Neuronal Cell Death and Scopolamine-Induced Memory Impairment
topicPhosphatidylserine Stress Randomized Trial
claimExposure to 0.3 mM HOfor 24 h markedly reduced cell viability andmRNA levels relative to those in the untreated control group, confirming the successful induction of oxidative cytotoxicity.
evidence level4
citationOh Kang-Il (2026)
sourceNeuroprotective Effect of the Combined Extract of Mentha piperita and Cornus officinalis Against Neuronal Cell Death and Scopolamine-Induced Memory Impairment
topicPhosphatidylserine Stress Randomized Trial
claim1 2 3 4 5 6 Mild cognitive impairment (MCI) refers to more than normal cognitive decline with age, yet insufficient to warrant a diagnosis of dementia [].
evidence level4
citationOh Kang-Il (2026)
sourceNeuroprotective Effect of the Combined Extract of Mentha piperita and Cornus officinalis Against Neuronal Cell Death and Scopolamine-Induced Memory Impairment