topicPeppermint Oil Bloating Randomized Trial
claimYoung adults, particularly females, have a higher prevalence, which has increased substantially over the past decades [].
evidence level2
citationPastras Ploutarchos (2026)
sourcePlant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines
topicPeppermint Oil Bloating Randomized Trial
claimMore specifically, the presence of recurrent abdominal pain, on average, at least 1 day per week in the last 3 months, associated with two or more of the following: symptoms related to defecation, a change in stool frequency, or a change in stool form [].
evidence level2
citationPastras Ploutarchos (2026)
sourcePlant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines
topicPeppermint Oil Bloating Randomized Trial
claimIBS is associated with reduced engagement in daily activities, increased work absenteeism, and impaired functioning, thereby increasing the global healthcare burden [].
evidence level2
citationPastras Ploutarchos (2026)
sourcePlant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines
topicPeppermint Oil Bloating Randomized Trial
claim1 2 1 3 1 4 5 Disorders of gut–brain interaction (DGBIs) are functional gastrointestinal conditions characterized by a complex interplay between the gut and the brain [].
evidence level2
citationPastras Ploutarchos (2026)
sourcePlant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines
topicPeppermint Oil Bloating Randomized Trial
claim1 2 3 4 5 5 6 7 6 7 Irritable bowel syndrome (IBS) is a chronic disorder of gut–brain interaction characterized by recurrent abdominal pain associated with altered bowel habits, in the absence of identifiable structural abnormalities [].
evidence level3
citationŠuran Jelena (2026)
sourceIBS and SIBO: Gut Microbiota, Pathophysiology, and Non-Pharmacological Interventions
topicPeppermint Oil Bloating Randomized Trial
claimEarly studies reported SIBO in up to 60–78% of IBS cases based on lactulose breath testing [,,], though later investigations using more rigorous methods found lower prevalences (e.g., 4–20%) [,].
evidence level3
citationŠuran Jelena (2026)
sourceIBS and SIBO: Gut Microbiota, Pathophysiology, and Non-Pharmacological Interventions
topicPeppermint Oil Bloating Randomized Trial
claimMoreover, increasing evidence implicating the gut microbiota in IBS/SIBO has spurred interest in interventions that modulate microbial communities.
evidence level3
citationŠuran Jelena (2026)
sourceIBS and SIBO: Gut Microbiota, Pathophysiology, and Non-Pharmacological Interventions
topicPeppermint Oil Bloating Randomized Trial
claimIt affects an estimated 5–10% of the global population and is more common in women, imposing a significant burden on quality of life and healthcare resources [].
evidence level3
citationŠuran Jelena (2026)
sourceIBS and SIBO: Gut Microbiota, Pathophysiology, and Non-Pharmacological Interventions