Peppermint Gut Health Randomized Trial Evidence Table

Structured evidence table for Peppermint Gut Health Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Peppermint Gut Health Randomized TrialEvidence from recent systematic reviews and meta-analyses consistently indicates that peppermint oil is the most effective botanical agent, particularly for reducing abdominal pain and overall IBS symptom severity.2Pastras P (2026)Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines.
Peppermint Gut Health Randomized TrialThe aim of this review is to summarize, compare, and critically evaluate all plant extracts studied for the prevention and treatment of IBS, integrating mechanistic pathways, clinical evidence, and current international guideline recommendations to clarify their therapeutic relevance for clinical practice.2Pastras P (2026)Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines.
Peppermint Gut Health Randomized TrialIrritable Bowel Syndrome (IBS) affects 4-15% of the global population, and the limited efficacy of existing pharmacologic therapies has driven growing interest in plant-based therapeutic options among both patients and clinicians.2Pastras P (2026)Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines.
Peppermint Gut Health Randomized TrialA comprehensive assessment of all plant extracts investigated in IBS is therefore essential, given the limited effectiveness of conventional treatments and the increasing interest in complementary approaches.2Pastras P (2026)Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines.
Peppermint Gut Health Randomized Trial1 2 3 4 5 5 6 7 6 7 Irritable bowel syndrome (IBS) is a chronic disorder of gut–brain interaction characterized by recurrent abdominal pain associated with altered bowel habits, in the absence of identifiable structural abnormalities [].3Šuran Jelena (2026)IBS and SIBO: Gut Microbiota, Pathophysiology, and Non-Pharmacological Interventions
Peppermint Gut Health Randomized TrialEarly studies reported SIBO in up to 60–78% of IBS cases based on lactulose breath testing [,,], though later investigations using more rigorous methods found lower prevalences (e.g., 4–20%) [,].3Šuran Jelena (2026)IBS and SIBO: Gut Microbiota, Pathophysiology, and Non-Pharmacological Interventions
Peppermint Gut Health Randomized TrialMoreover, increasing evidence implicating the gut microbiota in IBS/SIBO has spurred interest in interventions that modulate microbial communities.3Šuran Jelena (2026)IBS and SIBO: Gut Microbiota, Pathophysiology, and Non-Pharmacological Interventions
Peppermint Gut Health Randomized TrialIt affects an estimated 5–10% of the global population and is more common in women, imposing a significant burden on quality of life and healthcare resources [].3Šuran Jelena (2026)IBS and SIBO: Gut Microbiota, Pathophysiology, and Non-Pharmacological Interventions

Source documents

  1. Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines.
  2. IBS and SIBO: Gut Microbiota, Pathophysiology, and Non-Pharmacological Interventions