Structured evidence table for Passionflower Anxiety Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Passionflower Anxiety Randomized Trial | This narrative review critically evaluates clinical evidence on commonly used herbal preparations, with particular emphasis on herb-drug interactions, adverse effects, and issues related to product adulteration. | 3 | Căuș MN (2026) | Efficacy and Safety of Herbal Supplements with Anxiolytic, Antidepressant, and Sedative Action: A Review of Clinical Data and Toxicological Risks. |
| Passionflower Anxiety Randomized Trial | However, clinically relevant risks were identified, including cytochrome P450-mediated drug interactions, excessive sedation, serotonin syndrome, and toxic effects associated with adulterated products, such as hepatotoxicity, cardiovascular events, and neurological disturbances. | 3 | Căuș MN (2026) | Efficacy and Safety of Herbal Supplements with Anxiolytic, Antidepressant, and Sedative Action: A Review of Clinical Data and Toxicological Risks. |
| Passionflower Anxiety Randomized Trial | Increased awareness of herb-drug interactions and stricter quality control are essential to optimize therapeutic outcomes and minimize harm. | 3 | Căuș MN (2026) | Efficacy and Safety of Herbal Supplements with Anxiolytic, Antidepressant, and Sedative Action: A Review of Clinical Data and Toxicological Risks. |
| Passionflower Anxiety Randomized Trial | Background/Objectives: Plant-based supplements are widely used for the management of anxiety, depression, and insomnia. | 3 | Căuș MN (2026) | Efficacy and Safety of Herbal Supplements with Anxiolytic, Antidepressant, and Sedative Action: A Review of Clinical Data and Toxicological Risks. |
| Passionflower Anxiety Randomized Trial | These disturbances occur despite adequate opportunity and conditions for sleep [], and they result in general dissatisfaction with sleep quality and various daytime impairments. | 3 | Żełabowski Kacper (2025) | The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, Ramelteon, Agomelatine, and Selected Herbs |
| Passionflower Anxiety Randomized Trial | Individuals reporting nighttime symptoms without associated daytime dysfunction are not classified as having clinical insomnia [,]. | 3 | Żełabowski Kacper (2025) | The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, Ramelteon, Agomelatine, and Selected Herbs |
| Passionflower Anxiety Randomized Trial | Studies have demonstrated a direct correlation between inadequate sleep and an increased risk of developing metabolic diseases, such as diabetes, obesity, hypertension, cardiovascular disease, and depression [,,]. | 3 | Żełabowski Kacper (2025) | The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, Ramelteon, Agomelatine, and Selected Herbs |
| Passionflower Anxiety Randomized Trial | 1 2 2 3 4 3 5 6 6 4 6 The etymology of the term “insomnia” derives from Latin, combining “in” meaning “not” and “somnus,” meaning “sleep” []. | 3 | Żełabowski Kacper (2025) | The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, Ramelteon, Agomelatine, and Selected Herbs |
Source documents