topicOlive Leaf Cardiometabolic Markers Meta-Analysis
claimWe assessed the data for risk of bias, heterogeneity, sensitivity, reporting bias and quality of evidence.
evidence level1
citationIsmail MA (2021)
sourceOlive leaf extract effect on cardiometabolic profile among adults with prehypertension and hypertension: a systematic review and meta-analysis.
topicOlive Leaf Cardiometabolic Markers Meta-Analysis
claimNo significant changes were found between systolic or diastolic blood pressure (BP) for the first comparison, 1,000 mg per day for a combined formulation of olive leaf extract versus a placebo.
evidence level1
citationIsmail MA (2021)
sourceOlive leaf extract effect on cardiometabolic profile among adults with prehypertension and hypertension: a systematic review and meta-analysis.
topicOlive Leaf Cardiometabolic Markers Meta-Analysis
claimConclusions The results from this review suggest the reduction of systolic BP, LDL and inflammatory biomarkers, but it may not provide a robust conclusion regarding the effects of olive leaf extract on cardiometabolic profile due to the limited number of participants in the included trials.
evidence level1
citationIsmail MA (2021)
sourceOlive leaf extract effect on cardiometabolic profile among adults with prehypertension and hypertension: a systematic review and meta-analysis.
topicOlive Leaf Cardiometabolic Markers Meta-Analysis
claimBackground This systematic review and meta-analysis aimed to determine the effectiveness of olive leaf extract on cardiometabolic profiles among prehypertensive and hypertensive groups.
evidence level1
citationIsmail MA (2021)
sourceOlive leaf extract effect on cardiometabolic profile among adults with prehypertension and hypertension: a systematic review and meta-analysis.
topicOlive Leaf Cardiometabolic Markers Meta-Analysis
claimFurthermore, the treatment with the oil mixture (2.5 mL/Kg) and OLE (100 mg/Kg) to 24 month old Wistar rats for 21 days improved the lipid profile, increased the HOMA-IR and decreased the serum levels of miRNAs 21 and 146a.
evidence level4
citationGonzález-Hedström D (2021)
sourceAddition of Olive Leaf Extract to a Mixture of Algae and Extra Virgin Olive Oils Decreases Fatty Acid Oxidation and Synergically Attenuates Age-Induced Hypertension, Sarcopenia and Insulin Resistance in Rats.
topicOlive Leaf Cardiometabolic Markers Meta-Analysis
claimIn conclusion, treatment with a new nutraceutical based on a mixture of EVOO, AO and OLE is a useful strategy for improving the stability of n-3 PUFA in the final product and to attenuate the cardiometabolic and muscular disorders associated with aging.
evidence level4
citationGonzález-Hedström D (2021)
sourceAddition of Olive Leaf Extract to a Mixture of Algae and Extra Virgin Olive Oils Decreases Fatty Acid Oxidation and Synergically Attenuates Age-Induced Hypertension, Sarcopenia and Insulin Resistance in Rats.
topicOlive Leaf Cardiometabolic Markers Meta-Analysis
claimOlive-derived products, such as virgin olive oil (EVOO) and/or olive leaf extracts (OLE), exert anti-inflammatory, insulin-sensitizing and antihypertensive properties and may be useful for stabilizing omega 3 fatty acids (n-3 PUFA) due to their high content in antioxidant compounds.
evidence level4
citationGonzález-Hedström D (2021)
sourceAddition of Olive Leaf Extract to a Mixture of Algae and Extra Virgin Olive Oils Decreases Fatty Acid Oxidation and Synergically Attenuates Age-Induced Hypertension, Sarcopenia and Insulin Resistance in Rats.
topicOlive Leaf Cardiometabolic Markers Meta-Analysis
claimIn this study, the addition of OLE 4:0.15 ( w /w ) to a mixture of algae oil (AO) rich in n-3 PUFA and EVOO (25:75, w / w ) prevents peroxides formation after 12 months of storage at 30 °C.
evidence level4
citationGonzález-Hedström D (2021)
sourceAddition of Olive Leaf Extract to a Mixture of Algae and Extra Virgin Olive Oils Decreases Fatty Acid Oxidation and Synergically Attenuates Age-Induced Hypertension, Sarcopenia and Insulin Resistance in Rats.