topicNutritional Yeast Fatigue Randomized Trial
claimHowever, clinical evidence linking their intake to site-specific upper respiratory mucosal immune health in humans remains limited.
evidence level2
citationKanno T (2026)
sourceDietary β-1,3/1,6-Glucan from Baker's Yeast Supports Upper Respiratory Mucosal Immune Health in Healthy Adults: Evidence from a Randomized, Double-Blind, Placebo-Controlled Trial.
topicNutritional Yeast Fatigue Randomized Trial
claimSC-BG intake also attenuated declines in s-IgA levels in the posterior oropharyngeal wall and nasopharynx and increased salivary lysozyme concentrations.
evidence level2
citationKanno T (2026)
sourceDietary β-1,3/1,6-Glucan from Baker's Yeast Supports Upper Respiratory Mucosal Immune Health in Healthy Adults: Evidence from a Randomized, Double-Blind, Placebo-Controlled Trial.
topicNutritional Yeast Fatigue Randomized Trial
claimBackground/Objective : Dietary polysaccharides are increasingly recognized as functional nutritional components that support human health through modulation of immune function.
evidence level2
citationKanno T (2026)
sourceDietary β-1,3/1,6-Glucan from Baker's Yeast Supports Upper Respiratory Mucosal Immune Health in Healthy Adults: Evidence from a Randomized, Double-Blind, Placebo-Controlled Trial.
topicNutritional Yeast Fatigue Randomized Trial
claimIt also critically evaluates the current level of evidence and highlights key limitations related to standardization, variability of extracts, and clinical applicability.
evidence level3
citationSadowska Anna (2026)
sourceMedicinal Mushrooms and Their Bioactive Compounds: From Traditional Use to Therapeutic Potential
topicNutritional Yeast Fatigue Randomized Trial
claimNotably, a fungus calledwas found among the belongings of the world’s oldest human mummy, estimated to be about 4000 years old.
evidence level3
citationSadowska Anna (2026)
sourceMedicinal Mushrooms and Their Bioactive Compounds: From Traditional Use to Therapeutic Potential
topicNutritional Yeast Fatigue Randomized Trial
claimGanoderma lucidum In Chinese culture, lingzhi () was celebrated as a superior tonic and a symbol of spiritual power and immortality, and was regarded as the “herb of spiritual potency,” associated with success, well-being, divine power, and long life.
evidence level3
citationSadowska Anna (2026)
sourceMedicinal Mushrooms and Their Bioactive Compounds: From Traditional Use to Therapeutic Potential
topicNutritional Yeast Fatigue Randomized Trial
claim1 Approximately 2.2 to 3.8 million fungal species have been identified worldwide, with about 2000 regarded as edible and over 200 recognized for their medicinal properties.
evidence level3
citationSadowska Anna (2026)
sourceMedicinal Mushrooms and Their Bioactive Compounds: From Traditional Use to Therapeutic Potential