topicNettle Allergy Randomized Trial
claimFurthermore, they have anticholinergic side effects such as dry mouth, double vision, and urinary discomfort and may increase the risk for Alzheimer’s disease particularly in the elderly (Fourzali et al.).
evidence level3
citationMarcus Wagih H. (2025)
sourceModulatory effects of bioactive natural compounds on pruritic pathways: mechanistic basis and therapeutic prospects
topicNettle Allergy Randomized Trial
claimAdditionally, chronic itching may be treated with other systemic therapies, such as anticonvulsants and antidepressants, but are associated with varied side effects and difficulty of dose control (Reszke et al.).
evidence level3
citationMarcus Wagih H. (2025)
sourceModulatory effects of bioactive natural compounds on pruritic pathways: mechanistic basis and therapeutic prospects
topicNettle Allergy Randomized Trial
claimFor these limitations of synthetic medications, the risk of drug interactions and hypersensitivity occurrence there is a high demand for exploring alternative and natural treatment approaches, especially in chronic cases with unknown reasons.
evidence level3
citationMarcus Wagih H. (2025)
sourceModulatory effects of bioactive natural compounds on pruritic pathways: mechanistic basis and therapeutic prospects
topicNettle Allergy Randomized Trial
claim2018a 2020 2024 2018 2022 2010 2022 2021 2016 2007 Pruritus or itching is the most common skin disorder, characterized by an irritating sensation that evokes a scratch.
evidence level3
citationMarcus Wagih H. (2025)
sourceModulatory effects of bioactive natural compounds on pruritic pathways: mechanistic basis and therapeutic prospects
topicNettle Allergy Randomized Trial
claimEmerging evidence supports the role of blueberry consumption in maintaining gut microbial homeostasis and modulating the microbiota–inflammation–immunity axis [].
evidence level4
citationVenter Carina (2025)
sourceBlueberry Consumption in Early Life and Its Effects on Allergy, Immune Biomarkers, and Their Association with the Gut Microbiome
topicNettle Allergy Randomized Trial
claimConsumption of a blueberry drink over six weeks significantly increased the abundance of Bifidobacterium species in healthy adults [].
evidence level4
citationVenter Carina (2025)
sourceBlueberry Consumption in Early Life and Its Effects on Allergy, Immune Biomarkers, and Their Association with the Gut Microbiome
topicNettle Allergy Randomized Trial
claimAberrant or suboptimal microbial colonization during this period has been associated with increased gut permeability, low-grade inflammation, and impaired innate immune responses.
evidence level4
citationVenter Carina (2025)
sourceBlueberry Consumption in Early Life and Its Effects on Allergy, Immune Biomarkers, and Their Association with the Gut Microbiome
topicNettle Allergy Randomized Trial
claim1 2 3 4 5 6 7 8 The complementary feeding period is a critical window for shaping infant diet, gut microbiota, and immune development.
evidence level4
citationVenter Carina (2025)
sourceBlueberry Consumption in Early Life and Its Effects on Allergy, Immune Biomarkers, and Their Association with the Gut Microbiome