evidence table
N-Acetylcysteine Exercise Recovery Randomized Trial Evidence Table
Structured evidence table for N-Acetylcysteine Exercise Recovery Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| N-Acetylcysteine Exercise Recovery Randomized Trial | 1 Aging is characterized by progressive physiological decline, including loss of skeletal muscle mass and function (Sarcopenia), reduced mitochondrial efficiency, and increased oxidative stress, all of which contribute to frailty and diminished quality of life in older adults (). | 3 | Wang Xiaolan (2026) | Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults |
| N-Acetylcysteine Exercise Recovery Randomized Trial | 1 2 3 4 5 By the age of 70, individuals may experience a 25%−30% reduction in muscle mass, which is strongly associated with impaired mobility, falls, and loss of independence (). | 3 | Wang Xiaolan (2026) | Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults |
| N-Acetylcysteine Exercise Recovery Randomized Trial | Low circulating glycine levels have been associated with insulin resistance, obesity, and higher cardiometabolic risk (,). | 3 | Wang Xiaolan (2026) | Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults |
| N-Acetylcysteine Exercise Recovery Randomized Trial | In this review, the term “older adults” generally refers to individuals aged ≥60 or ≥65 years, consistent with definitions used by the World Health Organization and most geriatric clinical trials. | 3 | Wang Xiaolan (2026) | Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults |
| N-Acetylcysteine Exercise Recovery Randomized Trial | —Which populations and contexts (training status, sex and age, dietary pattern and energy availability, heat or hypoxia, and congested competition schedules) shift the balance from benefit to risk? | 3 | Mănescu Dan Cristian (2026) | Antioxidants and Exercise: A Redox-Informed Framework for Training Adaptation, Performance, and Recovery |
| N-Acetylcysteine Exercise Recovery Randomized Trial | This review addresses that problem for athletes and practitioners seeking evidence-based guidance. | 3 | Mănescu Dan Cristian (2026) | Antioxidants and Exercise: A Redox-Informed Framework for Training Adaptation, Performance, and Recovery |
| N-Acetylcysteine Exercise Recovery Randomized Trial | Evidence is organized by outcome domain—training adaptations versus acute performance/recovery—and analyzed through moderators that matter in real programs: class of antioxidant, dose, timing relative to key sessions, training phase, and environmental stress. | 3 | Mănescu Dan Cristian (2026) | Antioxidants and Exercise: A Redox-Informed Framework for Training Adaptation, Performance, and Recovery |
| N-Acetylcysteine Exercise Recovery Randomized Trial | 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 For decades, exercise-generated reactive oxygen species (ROS) were framed as unavoidable by-products of metabolism whose damage should be “neutralized” [,,,,]. | 3 | Mănescu Dan Cristian (2026) | Antioxidants and Exercise: A Redox-Informed Framework for Training Adaptation, Performance, and Recovery |
Source documents